Annelation of lactam rings to 2,3,4,4a-tetrahydro-1H-carbazole derivatives

被引：0
|
作者：
Sackus, A [1 ]
Krikstolaityte, S [1 ]
Martynaitis, V [1 ]
机构：
[1] Kaunas Univ Technol, Dept Organ Chem, LT-3028 Kaunas, Lithuania
来源：
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII | 1999年 / 05期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In the reaction of 4a-methyl-2,3,4,4a-tetrahydro-1H-carbazole and its 6-methyl- and 6-bromosubslituted derivatives with 2-chloroacetamide respective 9-carbamoylmethyl-4a-methyl-2,3,4,4a-tetrahydro- 1H-carbazolium chlorides are formed, which can be cyclized into 5,6,7,7a-tetrahydro-1H,4H-imidazo[2, 1-k] carbazol-2(3H)-one derivatives. Reaction of 4a methyl-2,3,4, 4a-tetrahydro-1H-carbazole hydrochloride with acrylamide gives 4a-methyl-1,2,6,7,8,8a-hexahydro-5H-pyrimido [2,1-k]carbazol-3 (4H)-one. 7a,12-Dimethyl-3,4,4a,5,6,7,7a,12-octahydropyrido [3,2-j]carbazol-2(1H)-one was synthesized by the reaction of 4a,9-dimethyl-2,3,4,4a-tetrahydro-9H-carbazole with acrylamide.
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页码：645 / 648
页数：4
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