Longitudinal MRI study of the midline brain regions in first-episode schizophrenia

被引：13

作者：

Takahashi, Tsutomu ^{[1
,2
]}

Nakamura, Kazue ^{[1
]}

Ikeda, Eiji ^{[1
]}

Furuichi, Atsushi ^{[1
]}

Kido, Mikio ^{[1
]}

Nakamura, Yumiko ^{[1
]}

Kawasaki, Yasuhiro ^{[4
]}

Noguchi, Kyo ^{[3
]}

Seto, Hikaru ^{[3
]}

Suzuki, Michio ^{[1
,2
]}

机构：

[1] Toyama Univ, Dept Neuropsychiat, Toyama 930, Japan

[2] Japan Sci & Technol Agcy, Core Res Evolut Sci & Technol, Tokyo, Japan

[3] Toyama Univ, Dept Radiol, Toyama 930, Japan

[4] Kanazawa Med Univ, Dept Neuropsychiat, Kanazawa, Ishikawa, Japan

来源：

PSYCHIATRY RESEARCH-NEUROIMAGING | 2013年 / 212卷 / 02期

关键词：

Adhesio interthalamica; Cavum septi pellucidi; Magnetic resonance imaging; CAVUM SEPTI PELLUCIDI; ULTRA-HIGH-RISK; ADHESIO INTERTHALAMICA; PSYCHOTIC DISORDERS; SPECTRUM DISORDERS; MASSA INTERMEDIA; PREVALENCE; INDIVIDUALS;

D O I：

10.1016/j.pscychresns.2012.12.001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

This magnetic resonance imaging (MRI) study investigated the prevalence and size of the adhesio interthalamica (AI) and cavum septi pellucidi (CSP) in 64 first-episode schizophrenia patients and 64 controls, of whom longitudinal data were available for 20 patients and 21 controls. The AI was shorter in the patients and showed longitudinal decline in both groups; there was also a trend for AI atrophy to correlate with negative symptoms. The CSP showed no group difference. These results suggest a role for the AI as a possible neurodevelopmental marker of schizophrenia. (c) 2012 Elsevier Ireland Ltd. All rights reserved.

引用

页码：150 / 153

页数：4

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