Benzimidazole and imidazopyridine derivatives as dopamine D-3 receptor antagonists for the treatment of psychosis

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作者：
不详
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来源：
EXPERT OPINION ON THERAPEUTIC PATENTS | 1996年 / 6卷 / 07期
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中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A series of benzimidazole and imidazopyridine derivatives are claimed in this patent to have utility in the treatment of neuropsychiatric conditions, especially schizophrenia and related psychoses. This claim is based on nanomolar affinities of these compounds for the dopamine D-3 receptor, and the relative selectivity of these agents for the D-3 vs. the D-2 receptor.
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页码：673 / 675
页数：3
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