Retinopathy of Prematurity - Pathophysiologic Mechanisms and New Treatment Options

被引：0
|
作者：
Stahl, A. [1 ]
Aisenbrey, S. [2 ]
Krohne, T. U. [3 ]
机构：
[1] Univ Freiburg, Univ Augenklin, D-79106 Freiburg, Germany
[2] Univ Tubingen, Univ Augenklin, Tubingen, Germany
[3] Univ Bonn, Univ Augenklin, Bonn, Germany
来源：
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE | 2012年 / 229卷 / 10期
关键词：
retina; retinopathy of prematurity; ROP; ENDOTHELIAL GROWTH-FACTOR; DIODE-LASER TREATMENT; LONGITUDINAL POSTNATAL WEIGHT; PROLIFERATIVE RETINOPATHY; RETINAL NEOVASCULARIZATION; INTRAVITREAL BEVACIZUMAB; VEGF; PREDICTOR; INFANTS; GAIN;
D O I：
10.1055/s-0032-1315247
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Retinopathy of prematurity (ROP), like other angioproliferative retinal disorders, has witnessed the advent of anti-VEGF therapy in clinical practice. The first report from the BEAT-ROP study published in 2011 represents the first comparison of anti-VEGF therapy versus conventional laser treatment in a randomised controlled trial. This review article investigates these novel aspects of ROP therapy from a pathophysiological angle and delineates the stages of ROP in which anti-VEGF treatment appears as a reasonable option. Furthermore, the novel chances of anti-VEGF therapy are being weighed against some still unanswered questions and novel study concepts are being presented.
引用
收藏
页码：1024 / 1029
页数：6
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