Induced interstitial pneumonitis:: role of pegylated interferon alpha 2b

被引：0

作者：

Rocca, P

Dumortier, J

Tanière, P

Duperret, S

Vial, T

Cottin, V

Delafosse, B

Scoazec, JY

Boillot, O

机构：

[1] Hop Edouard Herriot, Federat Specialites Digest, F-69437 Lyon 03, France

[2] Hop Edouard Herriot, Unite Transplantat Hepat, F-69437 Lyon, France

[3] Hop Edouard Herriot, Serv Anat & Cytol Pathol, F-69437 Lyon 03, France

[4] Hop Edouard Herriot, Dept Reanimat, F-69437 Lyon 03, France

[5] Hop Edouard Herriot, Dept Pharmacovigilance, F-69437 Lyon 03, France

[6] Hop Cardiovasc & Pneumol Louis Pradel, Serv Pneumol, Lyon, France

来源：

GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE | 2002年 / 26卷 / 04期

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Pulmonary complications of alpha interferon are rare. We report two cases of lung complications in liver transplantation patients for HCV related cirrhosis. After switching from interferon alpha to pegylated interferon alpha 2b, one patient developed a BOOP (Bronchiolitis Obliterans Organizing Pneumonia) and the other severe interstitial pneumonitis. We discuss the causes of these rare pulmonary alpha-interferon induced complications and the different way to suggest that the pegylated interferon alpha 2b could be related to the risk of pulmonary toxicity of this treatment.

引用

页码：405 / 408

页数：4

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