CCR2 INHIBITION IN DIABETIC BKS DB/DB MICE RESULTS IN A RAPID AND ROBUST IMPROVEMENT OF RENAL INFLAMMATION AND RENAL FUNCTION

被引：0
|
作者：
Jaen, Juan C. [1 ]
Sullivan, Timothy J. [1 ]
Miao, Zhenhua [1 ]
Zhao, Niky [1 ]
Berahovich, Rob [1 ]
Krasinski, Antoni [1 ]
Powers, Jay P. [1 ]
Ertl, Linda [1 ]
Schall, Thomas J. [1 ]
机构：
[1] Chemocentryx Inc, Mountain View, CA USA
来源：
NEPHROLOGY DIALYSIS TRANSPLANTATION | 2012年 / 27卷
关键词：
D O I：
暂无
中图分类号：
R3 [基础医学]; R4 [临床医学];
学科分类号：
1001 ; 1002 ; 100602 ;
摘要：
引用
收藏
页码：163 / 163
页数：1
相关论文
共 50 条
  • [1] CCR2 Inhibition Improves Renal Function in Diabetic BKS db/db Mice
    Sullivan, Timothy J.
    Miao, Zhenhua
    Zhao, Bin N.
    Berahovich, Robert D.
    Powers, Jay P.
    Ertl, Linda
    Jaen, Juan C.
    Schall, Thomas J.
    DIABETES, 2012, 61 : A133 - A133
  • [2] Inhibition of the CCR2 chemokine receptor in diabetic mice results in a rapid and robust improvement of hyperglycaemia
    Jaen, J. C.
    Miao, Z.
    Zhao, N.
    Berahovich, R.
    Ertl, L.
    Baumgart, T.
    Krasinski, A.
    Greenman, K.
    Bekker, P.
    Powers, J.
    Schall, T. J.
    Sullivan, T.
    DIABETOLOGIA, 2011, 54 : S365 - S365
  • [3] Inhibition of CCR2 Ameliorates Insulin Resistance and Hepatic Steatosis in db/db Mice
    Tamura, Yukinori
    Sugimoto, Masayuki
    Murayama, Toshinori
    Ueda, Yukihiko
    Kanamori, Hiroshi
    Ono, Koh
    Ariyasu, Hiroyuki
    Akamizu, Takashi
    Kita, Toru
    Yokode, Masayuki
    Arai, Hidenori
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2008, 28 (12) : 2195 - 2201
  • [4] Pancreatic kallikrein protects renal function in db/db diabetic mice
    Liu, Wenjuan
    Lu, Xiaolan
    Yang, Hui
    Hu, Ji
    Hu, Renming
    Zhang, Zhaoyun
    DIABETES-METABOLISM RESEARCH AND REVIEWS, 2014, 30 : 33 - 33
  • [5] CCR2 inhibition improves renal function in diabetic BTBR ob/ob Mice
    Sullivan, T. J.
    Miao, Z.
    Berahovich, R.
    Zhao, B. N.
    Ertl, L.
    Baumgart, T.
    Krasinski, A.
    Dang, T.
    Miao, S.
    Powers, J. P.
    Jaen, J. C.
    Schall, T. J.
    DIABETOLOGIA, 2012, 55 : S19 - S19
  • [6] Blockade of CCL2/CCR2 signalling ameliorates diabetic nephropathy in db/db mice
    Seok, Su Jin
    Lee, Eun Soo
    Kim, Geun Tae
    Hyun, Miri
    Lee, Ji-Hye
    Chen, Sheldon
    Choi, Ran
    Kim, Hong Min
    Lee, Eun Young
    Chung, Choon Hee
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2013, 28 (07) : 1700 - 1710
  • [7] Blockade of CCL2/CCR2 Signalling Ameliorates Diabetic Nephropathyin db/db Mice
    Lee, Eun Young
    Seok, Su Jin
    Lee, Eun Soo
    Lee, Ji-Hye
    Kim, Hong Min
    Kim, Yeo Joo
    Chen, Sheldon
    Chung, Choon Hee
    DIABETES, 2013, 62 : A132 - A132
  • [8] Prevention of decline in renal function in the diabetic db/db mouse
    Cohen, MP
    Clements, RS
    Cohen, JA
    Shearman, CW
    DIABETOLOGIA, 1996, 39 (03) : 270 - 274
  • [9] Aliskiren and/or vitamin D suppress renal inflammation in db/db mice
    Takenaka, Tsuneo
    Inoue, Tsutomu
    Ohno, Yoichi
    Miyazaki, Takashi
    Suzuki, Hiromichi
    FASEB JOURNAL, 2013, 27
  • [10] RENAL PROTECTIVE EFFECT OF THALIDOMIDE IN DIABETIC NEPHROPATHY IN DB/DB MICE
    Duan, Qi
    Guo, Lili
    Xu, Weiwei
    Wang, Qian
    Xin, Xiaohong
    Li, Yafeng
    NEPHROLOGY, 2020, 25 : 60 - 61
12345