FIVE VARIANTS OF THE β-GLOBIN GENE WITHOUT CLINICAL OR HEMATOLOGICAL EFFECTS: Hb MARYLAND [β47(CD6)Asp→His], Hb KENT [β37(C3)Trp→Cys], Hb VISAYAN [β136(H14)Gly→Cys], Hb CUTLERVILLE [β138(H16)Ala→Val] AND Hb HORNCHURCH [β43(CD2)Glu→Lys]

被引：6

作者：

Hoyer, James D.

Kaur, Prabhjot

Kozak, Elizabeth A.

Lum, Sophia

Alter, David N.

机构：

[1] Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

[2] Spectrum Health, Grand Rapids, MI

[3] Department of Primary Care, Southern California Permanente Medical Group, Carlsbad, CA

[4] Department of Laboratory Medicine and Pathology, Mayo Clinic, 816 Hilton Building, Rochester, MN 55905

来源：

HEMOGLOBIN | 2008年 / 32卷 / 05期

关键词：

D O I：

10.1080/03630260802341901

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We report on five hemoglobin (Hb) beta chain variants that were initially identified either by electrophoretic, chromatographic or isoelectric focusing (IEF) methods. These variants do not appear to be associated with clinical or hematological abnormalities. All variants were confirmed by DNA sequence analysis.

引用

页码：471 / 477

页数：7