Clinical Aspects and Management of Levodopa-Induced Dyskinesia

被引：19

作者：

Tambasco, Nicola ^{[1
]}

Simoni, Simone ^{[1
]}

Marsili, Erica ^{[1
]}

Sacchini, Elisa ^{[1
]}

Murasecco, Donatella ^{[1
]}

Cardaioli, Gabriela ^{[1
]}

Rossi, Aroldo ^{[1
]}

Calabresi, Paolo ^{[1
,2
]}

机构：

[1] Univ Perugia, Azienda Osped, Neurol Clin, I-06156 Perugia, Italy

[2] Fdn S Lucia, IRCCS, I-00179 Rome, Italy

来源：

PARKINSONS DISEASE | 2012年 / 2012卷

关键词：

ADVANCED PARKINSONS-DISEASE; 24-HOUR PROLONGED RELEASE; DOPA-INDUCED DYSKINESIA; SUBTHALAMIC NUCLEUS STIMULATION; ADENOSINE A(2A) RECEPTORS; PLACEBO-CONTROLLED TRIAL; 10-YEAR FOLLOW-UP; DOUBLE-BLIND; MOTOR FLUCTUATIONS; ADJUNCTIVE THERAPY;

D O I：

10.1155/2012/745947

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In Parkinson's disease, one of the most troublesome dilemmas is the treatment of levodopa-induced dyskinesia. After a few years, chronic treatment with levodopa is associated with the development of dyskinesias. Strategies to delay or to reduce dyskinesias are based on the change of levodopa dosing or the early use of dopamine agonists. Dopamine agonists with different pharmacological profile are available. Our paper was aimed to analyse the clinical impact and the management of dyskinesias with dopamine agonists.

引用

页数：12

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