Efficient iron-catalyzed Michael addition of indole to nitroolefins under solvent-free conditions

被引：11
|
作者：
Liang, Lei [1 ]
Liu, Qiang [1 ]
Zhang, Jianli [1 ]
Wang, Fengyuan [1 ]
Yuan, Yu [2 ]
机构：
[1] Liaoning Univ, Coll Environm, Shenyang 110036, Liaoning, Peoples R China
[2] Yangzhou Univ, Coll Chem & Chem Engn, Yangzhou 225002, Peoples R China
来源：
RESEARCH ON CHEMICAL INTERMEDIATES | 2013年 / 39卷 / 05期
关键词：
Catalytic reactions; FeCl3 center dot 6H(2)O; Green chemistry; Michael addition; Organic synthesis; ATOM TRANSFER; CYCLOALKENONES; NITROALKENES; DERIVATIVES; ALCOHOLS; FRIEDEL; COMPLEX; THIOLS;
D O I：
10.1007/s11164-012-0728-1
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Iron trichloride hexahydrate has proved to be an effective catalyst for Michael addition of indole to nitroolefins under solvent-free conditions to produce the corresponding adducts with appreciable yields. Solvent-free Michael addition of indole to nitroolefins with 0.01 mol% iron(III) chloride, affording the corresponding adduct compounds in high yields (up to 97 %).
引用
收藏
页码：1957 / 1962
页数：6
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