Infliximab-induced lupus-like syndrome in a patient with ankylosing spondylitis

被引:8
|
作者
Bodur, Hatice [1 ]
Eser, Filiz [1 ]
Konca, Sefika [1 ]
Arikan, Serpil [2 ]
机构
[1] Ankara Numune Training & Res Hosp, Dept Phys Med & Rehabil, Ankara, Turkey
[2] Ankara Numune Training & Res Hosp, Dept Chest Dis, Ankara, Turkey
关键词
Drug-induced lupus; Ankylosing spondylitis; Anti-TNF agents; NECROSIS-FACTOR; ERYTHEMATOSUS; DISEASES; EFFICACY; THERAPY; SAFETY;
D O I
10.1007/s00296-008-0684-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Infliximab is a chimerical monoclonal antibody currently used in the treatment of various inflammatory diseases. Lupus-like syndrome is a rarely reported adverse event, and generally observed in rheumatoid arthritis cases. We hereby define and describe a case of a lupus-like syndrome, which developed following the 4th infliximab infusion in a 62-year-old patient with ankylosing spondylitis (AS). As far as we acknowledge, the present case is the third AS case with infliximab-induced lupus.
引用
收藏
页码:451 / 454
页数:4
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