Metabolic engineering: enabling technology of a bio-based economy

被引：14

作者：

Zhang, Jie ^{[1
]}

Babtie, Ann ^{[1
]}

Stephanopoulos, Gregory ^{[1
]}

机构：

[1] MIT, Dept Chem Engn, Cambridge, MA 02139 USA

来源：

CURRENT OPINION IN CHEMICAL ENGINEERING | 2012年 / 1卷 / 04期

关键词：

L-TYROSINE PRODUCTION; L-LYSINE PRODUCTION; ESCHERICHIA-COLI; CORYNEBACTERIUM-GLUTAMICUM; PATHWAY; BIOSYNTHESIS; MICROORGANISMS; OVERPRODUCTION; EXPRESSION; CONVERSION;

D O I：

10.1016/j.coche.2012.09.003

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Concerns about future oil supplies and climate change are fueling interest in sustainable alternative sources of energy and chemicals. Biomass is a renewable feedstock that has the potential to replace a significant fraction of petroleum used today. Advances in metabolic engineering and biotechnology have made it possible to engineer microorganisms capable of converting simple sugars derived from various sources including cellulosic feedstocks into a diverse range of products. We highlight the potential of this approach to produce cost effective biosynthetic routes to fuels, chemicals and pharmaceuticals in an envisioned future bio-based economy.

引用

页码：355 / 362

页数：8

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