Synthesis and antimicrobial activity of novel gold(I) N-heterocyclic carbene complexes

被引：11
|
作者：
Dogan, Oznur [1 ]
Kaloglu, Nazan [1 ]
Demir, Serpil [1 ]
Ozdemir, Ilknur [1 ]
Gunal, Selami [2 ]
Ozdemir, Ismail [1 ]
机构：
[1] Inonu Univ, Fac Sci, Dept Chem, TR-44280 Malatya, Turkey
[2] Inonu Univ, Fac Pharm, Dept Microbiol, TR-44280 Malatya, Turkey
来源：
MONATSHEFTE FUR CHEMIE | 2013年 / 144卷 / 03期
关键词：
Gold-NHC complexes; Medicinal inorganic chemistry; Antimicrobial; Benzimidazol-2-ylidene; C-H BONDS; PERMEABILITY TRANSITION; CATALYTIC-ACTIVITY; SILVER COMPLEXES; FACILE SYNTHESIS; LIGAND; CYTOTOXICITY; INHIBITION; AURANOFIN; PALLADIUM;
D O I：
10.1007/s00706-012-0812-7
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Benzimidazolium salts and six anionic gold-NHC complexes (NHC = N,N'-dialkylbenzimidazol-2-ylidene) were prepared and characterized. Novel [Au(NHC)(2)]AuCl2-type complexes were prepared in good yields from silver-NHC complexes by treatment with [AuCl(PPh3)], following the commonly used silver carbene transfer route. All compounds were characterized using H-1 and C-13 NMR spectroscopy, elemental analysis, and IR. The gold complexes showed antimicrobial activity against Gram-positive/negative and fungal strains.
引用
收藏
页码：313 / 319
页数：7
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