High-throughput single-cell targeted DNA sequencing from frozen, fixed and preserved solid tumor samples reveals complex genomic variation and clonal propagation

被引：0
|
作者：
Ruff, David [1 ]
Mendez, Pedro [1 ]
Mendoza, Daniel [1 ]
Li, Nianzhen [1 ]
Sciambi, Adam [1 ]
Gokhale, Kaustubh [1 ]
Dhingra, Dalia [1 ]
Jones, Keith [1 ]
Eastburn, Dennis [1 ]
机构：
[1] Mission Bio Inc, San Francisco, CA USA
来源：
CANCER RESEARCH | 2019年 / 79卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2019-2532
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2532
引用
收藏
页数：2
相关论文
共 42 条
  • [1] High-throughput single-cell targeted DNA sequencing using an updated Tapestri™ Platform reveals rare clones and clonal evolution for multiple blood cancers
    Li, Nianzhen
    Mendoza, Daniel
    Sciambi, Adam
    Manivannan, Mani
    Ho, Jacob
    Gokhale, Kaustubh
    Marin, Jacqueline
    Thompson, Kathryn
    Yates, Jamie
    Sharma, Vasu
    Chow, Steven
    Sahu, Sombeet
    Wang, Shu
    Eastburn, Dennis
    Jones, Keith
    CANCER RESEARCH, 2019, 79 (13)
  • [2] High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes
    Mandeep Singh
    Ghamdan Al-Eryani
    Shaun Carswell
    James M. Ferguson
    James Blackburn
    Kirston Barton
    Daniel Roden
    Fabio Luciani
    Tri Giang Phan
    Simon Junankar
    Katherine Jackson
    Christopher C. Goodnow
    Martin A. Smith
    Alexander Swarbrick
    Nature Communications, 10
  • [3] High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes
    Singh, Mandeep
    Al-Eryani, Ghamdan
    Carswell, Shaun
    Ferguson, James M.
    Blackburn, James
    Barton, Kirston
    Roden, Daniel
    Luciani, Fabio
    Tri Giang Phan
    Junankar, Simon
    Jackson, Katherine
    Goodnow, Christopher C.
    Smith, Martin A.
    Swarbrick, Alexander
    NATURE COMMUNICATIONS, 2019, 10 (1)
  • [4] Optimization of high-throughput, high-depth, targeted single-cell DNA sequencing to pancreatic ductal adenocarcinoma
    Zhang, Haochen
    Karnoub, Elias-Ramzey
    Chaligne, Ronan
    Masilionis, Ignas
    Makohon-Moore, Alvin
    Hong, Jungeui
    Iacobuzio-Donahue, Christine
    CANCER RESEARCH, 2022, 82 (12)
  • [5] Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations
    Tyler E. Miller
    Caleb A. Lareau
    Julia A. Verga
    Erica A. K. DePasquale
    Vincent Liu
    Daniel Ssozi
    Katalin Sandor
    Yajie Yin
    Leif S. Ludwig
    Chadi A. El Farran
    Duncan M. Morgan
    Ansuman T. Satpathy
    Gabriel K. Griffin
    Andrew A. Lane
    J. Christopher Love
    Bradley E. Bernstein
    Vijay G. Sankaran
    Peter van Galen
    Nature Biotechnology, 2022, 40 (7) : 1030 - 1034
  • [6] Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations
    Miller, Tyler E.
    Lareau, Caleb A.
    Verga, Julia A.
    DePasquale, Erica A. K.
    Liu, Vincent
    Ssozi, Daniel
    Sandor, Katalin
    Yin, Yajie
    Ludwig, Leif S.
    El Farran, Chadi A.
    Morgan, Duncan M.
    Satpathy, Ansuman T.
    Griffin, Gabriel K.
    Lane, Andrew A.
    Love, J. Christopher
    Bernstein, Bradley E.
    Sankaran, Vijay G.
    van Galen, Peter
    NATURE BIOTECHNOLOGY, 2022, 40 (07) : 1030 - +
  • [7] High-Throughput Single-Cell DNA Sequencing of AML Tumors with Droplet Microfluidics
    Eastburn, Dennis J.
    Pellegrino, Maurizio
    Sciambi, Adam
    Treusch, Sebastian
    Gokhale, Kaustubh
    Jacob, Jose
    Chen, Tina
    Matthews, Jairo
    Morita, Kiyomi
    Takahashi, Keith Jonesand Koichi
    BLOOD, 2017, 130
  • [8] High-Throughput Detection of Actionable Genomic Alterations in Clinical Tumor Samples by Targeted, Massively Parallel Sequencing
    Wagle, Nikhil
    Berger, Michael F.
    Davis, Matthew J.
    Blumenstiel, Brendan
    DeFelice, Matthew
    Pochanard, Panisa
    Ducar, Matthew
    Van Hummelen, Paul
    MacConaill, Laura E.
    Hahn, William C.
    Meyerson, Matthew
    Gabriel, Stacey B.
    Garraway, Levi A.
    CANCER DISCOVERY, 2012, 2 (01) : 82 - 93
  • [9] High-Throughput Single-Cell Targeted DNA Sequencing for Hematologic Cancers Using Droplet-Based Microfluidic Platform
    Liu, Benchun
    Li, Nianzhen
    Mendoza, Daniel
    Gokhale, Kaustubh
    Sciambi, Adam
    Manivannan, Mani
    Ho, Jacob
    Marin, Jacqueline
    Thompson, Kathryn
    Wang, Shu
    Sahu, Sombeet
    Gulati, Saurabh
    Nousheen, Lubna
    Carrerou, Florencia
    Chow, Steven
    Curt, Charles
    Jones, Keith
    Beard, Nigel
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2019, 19 : S221 - S221
  • [10] High-throughput unbiased microwell-based single-cell CNV detection reveals tumor clonal subtypes in hepatocellular carcinoma
    Wu, Liang
    Wang, Yuzhou
    Jiang, Miaomiao
    Liu, Shiping
    CANCER RESEARCH, 2019, 79 (13)
12345