Objective: The aim of this study was to analyze stepped rehabilitation nursing's ability to improve recovery from minimally invasive surgery and to examine the application of long-term activity function in patients with intervertebral disc herniation. Methods: A total of 124 patients with intervertebral disc herniation were collected as research subjects, including 74 males and 50 females. All patients were randomly divided into the research group (n=62), using stepped nursing intervention, and the control group (n=62), using routine nursing intervention, according to the random number table method. Rehabilitation and pain conditions, before and 5 days after the operation, were observed. Lumbar vertebra conditions were evaluated by JOA, Oswestry dysfunction indexes, and straight leg elevation tests. All patients were followed-up for one year. After one year, the patients were asked to return to the hospital for reviews. JOA, Oswestry dysfunction indexes, and straight leg elevation tests were used to evaluate the activity function of the two groups. Results: The rehabilitation rate of the research group was 96.77%, significantly higher than that of the control group (85.48%) (P=0.027). There were no significant differences in VAS, JOA, Oswestry dysfunction indexes, and straight leg elevation tests between the two groups before treatment (P > 0.050). After treatment, VAS scores and Oswestry dysfunction indexes of the research group were significantly lower than those of the control group (P < 0.001). JOA and excellent rates of straight leg elevation tests were significantly higher than those of the control group (P < 0.001). There were no significant differences in JOA, Oswestry dysfunction indexes, and excellent rates of straight leg elevation tests between the two groups in prognosis for 1 year (P > 0.050). Conclusion: Stepped nursing can effectively improve the effects of minimally invasive surgery for patients, displaying a better guarantee for patients with long-term activity ability.