Global Burden of Childhood Epilepsy, Intellectual Disability, and Sensory Impairments

被引：118

作者：

Olusanya, Bolajoko O. ^{[1
]}

Wright, Scott M. ^{[2
]}

Nair, M. K. C. ^{[3
]}

Boo, Nem-Yun ^{[4
]}

Halpern, Ricardo ^{[5
]}

Kuper, Hannah ^{[6
]}

Abubakar, Amina A. ^{[7
]}

Almasri, Nihad A. ^{[8
]}

Arabloo, Jalal ^{[9
]}

Arora, Narendra K. ^{[10
]}

Backhaus, Sophia ^{[11
]}

Berman, Brad D. ^{[12
,13
]}

Breinbauer, Cecilia ^{[14
]}

Carr, Gwen ^{[15
]}

de Vries, Petrus J. ^{[16
]}

del Castillo-Hegyi, Christie ^{[17
,18
]}

Eftekhari, Aziz ^{[19
]}

Gladstone, Melissa J. ^{[20
]}

Hoekstra, Rosa A. ^{[21
]}

Kancherla, Vijaya ^{[22
]}

Mulaudzi, Mphelekedzeni C. ^{[23
]}

Kakooza-Mwesige, Angelina ^{[24
]}

Ogbo, Felix A. ^{[25
]}

Olsen, Helen E. ^{[26
]}

Olusanya, Jacob O. ^{[1
]}

Pandey, Ashok ^{[27
]}

Samms-Vaughan, Maureen E. ^{[28
]}

Servili, Chiara ^{[29
]}

Shaheen, Amira ^{[30
]}

Smythe, Tracey ^{[6
]}

Wertlieb, Donald ^{[31
]}

Williams, Andrew N. ^{[32
]}

Newton, Charles R. J. ^{[7
]}

Davis, Adrian C. ^{[15
]}

Kassebaum, Nicholas J. ^{[33
]}

机构：

[1] Ctr Hlth Start Initiat, 286A Corp Dr, Lagos, Nigeria

[2] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA

[3] NIMS Med, NIMS Spectrum Child Dev Res Ctr, Thiruvananthapuram, Kerala, India

[4] Univ Tunku Abdul Rahman, Fac Med & Hlth Sci, Dept Populat Med, Kajang, Selangor, Malaysia

[5] Univ Hlth Sci Porto Alegre, Dept Pediat & Adolescence, Porto Alegre, RS, Brazil

[6] London Sch Hyg & Trop Med, Int Ctr Evidence Disabil, London, England

[7] Kenya Govt Med Res Ctr, Ctr Geog Med Res Coast, Wellcome Trust Res Programme, Kilifi, Kenya

[8] Univ Jordan, Sch Rehabil Sci, Dept Physiotherapy, Amman, Jordan

[9] Iran Univ Med Sci, Hlth Management & Econ Res Ctr, Tehran, Iran

[10] INCLEN Trust Int, New Delhi, India

[11] Univ Oxford, Dept Social Policy & Intervent, Ctr Evidence Based Intervent, Oxford, England

[12] Univ Calif San Francisco, Dept Pediat, Benioff Childrens Hosp, San Francisco, CA USA

[13] Progress Dev & Behav Pediat, San Francisco, CA USA

[14] Ctr Hlth Dev, Seattle, WA USA

[15] UCL, Ear Inst, London, England

[16] Univ Cape Town, Dept Psychiat & Mental Hlth, Div Child & Adolescent Psychiat, Cape Town, South Africa

[17] CHI St Vincent, Dept Emergency Med, Little Rock, AR USA

[18] Fed Is Best Fdn, Little Rock, AR USA

[19] Maragheh Univ Med Sci, Dept Pharmacol & Toxicol, Maragheh, Iran

[20] Univ Liverpool, Inst Translat Med, Liverpool, Merseyside, England

[21] Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Psychol, London, England

[22] Emory Univ, Dept Epidemiol, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA

[23] Univ Witwatersrand, Dept Paediat & Child Hlth, Johannesburg, South Africa

[24] Makerere Univ Coll Hlth Sci, Dept Paediat & Child Hlth, Kampala, Uganda

[25] Western Sydney Univ, Sch Med, Translat Hlth Res Inst, Campbelltown Campus, Penrith, NSW, Australia

[26] Bill & Melinda Gates Fdn, Seattle, WA USA

[27] Nepal Hlth Res Council, Kathmandu, Nepal

[28] Univ West Indies, Dept Child & Adolescent Hlth, Mona Campus, Kingston, Jamaica

[29] World Hlth Org, Dept Mental Hlth & Substance Use, Geneva, Switzerland

[30] An Najah Natl Univ, Fac Med & Hlth Sci, Div Publ Hlth, Nablus, Palestine

[31] Tufts Univ, Eliot Pearson Dept Child Dev, Medford, MA 02155 USA

[32] Northampton Gen Hosp, Virtual Acad Unit, Northampton, England

[33] Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA

来源：

PEDIATRICS | 2020年 / 146卷 / 01期

基金：

比尔及梅琳达.盖茨基金会;

关键词：

PREVALENCE;

D O I：

10.1542/peds.2019-2623

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

At least 291 million children and adolescents had disabilities in 2017 globally, which is substantially higher than the GBD estimate of 93 million in 2004. BACKGROUND:Estimates of children and adolescents with disabilities worldwide are needed to inform global intervention under the disability-inclusive provisions of the Sustainable Development Goals. We sought to update the most widely reported estimate of 93 million children <15 years with disabilities from the Global Burden of Disease Study 2004.METHODS:We analyzed Global Burden of Disease Study 2017 data on the prevalence of childhood epilepsy, intellectual disability, and vision or hearing loss and on years lived with disability (YLD) derived from systematic reviews, health surveys, hospital and claims databases, cohort studies, and disease-specific registries. Point estimates of the prevalence and YLD and the 95% uncertainty intervals (UIs) around the estimates were assessed.RESULTS:Globally, 291.2 million (11.2%) of the 2.6 billion children and adolescents (95% UI: 249.9-335.4 million) were estimated to have 1 of the 4 specified disabilities in 2017. The prevalence of these disabilities increased with age from 6.1% among children aged <1 year to 13.9% among adolescents aged 15 to 19 years. A total of 275.2 million (94.5%) lived in low- and middle-income countries, predominantly in South Asia and sub-Saharan Africa. The top 10 countries accounted for 62.3% of all children and adolescents with disabilities. These disabilities accounted for 28.9 million YLD or 19.9% of the overall 145.3 million (95% UI: 106.9-189.7) YLD from all causes among children and adolescents.CONCLUSIONS:The number of children and adolescents with these 4 disabilities is far higher than the 2004 estimate, increases from infancy to adolescence, and accounts for a substantial proportion of all-cause YLD.

引用

页数：17

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