Nitric oxide and cardiovascular protection

被引：12

作者：

Jugdutt, BL ^{[1
]}

机构：

[1] Univ Alberta, Walter McKenzie Hlth Sci Ctr 2C243, Div Cardiol, Dept Med, Edmonton, AB T6G 2R7, Canada

来源：

HEART FAILURE REVIEWS | 2003年 / 8卷 / 01期

关键词：

nitric oxide; cardiovascular protection; ischemic preconditioning;

D O I：

10.1023/A:1022190820131

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Nitric oxide (NO) plays a critical role in ischemic heart disease and ischemia-reperfusion. There is an increasing body of evidence to support the role of NO in myocardial and vascular protection in disease. The finding that NO might act as a trigger of late ischemic preconditioning (IPC) might lead to the development of novel anti-ischemic therapy. The role of NO signaling in the cardioprotective effects of ACE inhibitors and angiotensin II type 1 receptor(AT(1)) receptor antagonists is an active area of study.

引用

页码：29 / 34

页数：6

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