Microenvironmental SFRP1 controls repopulating activity of Hematopoietic Stem Cells via PP2A-mediated regulation of CTNNB1/EP300

被引：0
|
作者：
Hettler, F. [1 ]
Schreck, C. [1 ]
Marquez, Romero S. [1 ]
Sippenauer, T. [1 ]
Koller, F. [1 ]
Demir, E. [2 ]
Bassermann, F. [1 ]
Istvanffy, R. [2 ]
Oostendorp, R. [1 ]
机构：
[1] Tech Univ Munich, Klinikum Rechts Isar, Med Klin 3, Munich, Germany
[2] Tech Univ Munich, Klinikum Rechts Isar, Med Klin 2, Munich, Germany
来源：
ONCOLOGY RESEARCH AND TREATMENT | 2020年 / 43卷 / SUPPL 4期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
619
引用
收藏
页码：32 / 33
页数：2
相关论文
共 12 条
  • [1] MICROENVIRONMENTAL SFRP1 REGULATES REPOPULATING ACTIVITY OF HEMATOPOIETIC STEM CELLS VIA PP2A-MEDIATED REGULATION OF CTNNB1/EP300
    Hettler, Franziska
    Schreck, Christina
    Marquez, Sandra Romero
    Sippenauer, Theresa
    Koller, Franziska
    Demir, Ekin
    Bassermann, Florian
    Istvanffy, Rouzanna
    Oostendorp, Robert
    EXPERIMENTAL HEMATOLOGY, 2020, 88 : S31 - S31
  • [2] Osteoprogenitor SFRP1 prevents exhaustion of hematopoietic stem cells via PP2A-PR72/130-mediated regulation of p300
    Hettler, Franziska
    Schreck, Christina
    Marquez, Sandra Romero
    Engleitner, Thomas
    Vilne, Baiba
    Landspersky, Theresa
    Weidner, Heike
    Hausinger, Renate
    Mishra, Ritu
    Oellinger, Rupert
    Rauner, Martina
    Naumann, Ronald
    Peschel, Christian
    Bassermann, Florian
    Rad, Roland
    Istvanffy, Rouzanna
    Oostendorp, Robert A. J.
    HAEMATOLOGICA, 2023, 108 (02) : 490 - 501
  • [3] OSTEOPROGENITOR SFRP1 PREVENTS FUNCTIONAL DECLINE OF HEMATOPOIETIC STEM CELLS VIA PP2A-PR72/130-MEDIATED REGULATION OF P300
    Oostendorp, Robert
    Bassermann, Florian
    Hettler, Franziska
    Istvanffy, Rouzanna
    Landspersky, Theresa
    Naumann, Ronald
    Marquez, Sandra Romero
    Schreck, Christina
    EXPERIMENTAL HEMATOLOGY, 2022, 111 : S122 - S122
  • [4] CTNNB1 Signaling in Sertoli Cells Downregulates Spermatogonial Stem Cell Activity via WNT4
    Boyer, Alexandre
    Yeh, Jonathan R.
    Zhang, Xiangfan
    Paquet, Marilene
    Gaudin, Aurore
    Nagano, Makoto C.
    Boerboom, Derek
    PLOS ONE, 2012, 7 (01):
  • [5] Sustained CTNNB1 Signaling in Sertoli Cells Downregulates Spermatogonial Stem Cell Activity via WNT4
    Boyer, Alexandre
    Yeh, Jonathan R.
    Zhang, Xiangfan
    Nagano, Makoto C.
    Boerboom, Derek
    BIOLOGY OF REPRODUCTION, 2011, 85
  • [6] Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis
    Varier, Krishnapriya M.
    Dan, Gou
    Liu, Wuling
    Wu, Guoping
    Xiao, Chaoda
    Lei, Huang
    Ling, Tao
    Jiang, Yanping
    Chen, Ying
    Ben-David, Yaacov
    Li, Yanmei
    Zhang, Nenling
    Gajendran, Babu
    Shen, Xiangchun
    BIOMEDICINE & PHARMACOTHERAPY, 2022, 156
  • [7] TGF-β1 maintains Foxp3 expression and inhibits glycolysis in natural regulatory T cells via PP2A-mediated suppression of mTOR signaling
    Chen, Xuelu
    Feng, Li
    Li, Shengfu
    Long, Dan
    Shan, Juan
    Li, Youping
    IMMUNOLOGY LETTERS, 2020, 226 : 31 - 37
  • [8] SZT2 maintains hematopoietic stem cell homeostasis via nutrient-mediated mTORC1 regulation
    Yin, Na
    Jin, Gang
    Ma, Yuying
    Zhao, Hanfei
    Zhang, Guangyue
    Li, Ming O.
    Peng, Min
    JOURNAL OF CLINICAL INVESTIGATION, 2022, 132 (20):
  • [9] Dose-dependent toxicity of FTY720, a sphingosine-1-phosphate receptor agonist, on double hit lymphoma cells via PP2A-mediated dephosphorylation of c-myc and bcl-2
    Shouse, Geoffrey P.
    de Necochea-Campion, Rosalia
    Mirshahidi, Saied
    Chen, Chien-Shing
    Payne, Kimberly J.
    CANCER RESEARCH, 2018, 78 (13)
  • [10] Potential Targeting Ph+ Acute Lymphoblastic Leukemia Stem and Progenitor Cells By Modulating the CIP2A-SET-SETBP1-Mediated Suppression of PP2A Activity
    Yu, Justine
    Silvestri, Giovannino
    Stramucci, Lorenzo
    Sanada, Masashi
    Yamaguchi, Tomoyuki
    Du, Yang
    Westermarck, Jukka
    Caligiuri, Michael A.
    Garzon, Ramiro
    Milojkovic, Dragana
    Apperley, Jane F.
    Roy, Denis-Claude
    Marcucci, Guido
    Calabretta, Bruno
    Baer, Maria R.
    Trotta, Rossana
    Perrotti, Danilo
    BLOOD, 2016, 128 (22)
12