A facile synthesis of annulated azolo[c][1,2,4]thiadiazine S,S-dioxides

被引：3

作者：

Cherepakha, Artem ^{[1
]}

Kovtunenko, Vladimir O. ^{[1
]}

Tolmachev, Andrey ^{[2
]}

机构：

[1] Natl Tarns Shevchenko Univ, ChemBioCtr, UA-01033 Kiev, Ukraine

[2] Enamine Ltd, UA-01103 Kiev, Ukraine

来源：

TETRAHEDRON LETTERS | 2013年 / 54卷 / 08期

关键词：

Azolo[c][1,2,4]benzothiadiazine S,S-dioxides; Sulfonyl chlorides; 3-Aminoazoles; Copper(I) iodide; (1,2,4)-BENZOTHIADIAZIN-5,5-DIOXIDS; DERIVATE; SYSTEMS;

D O I：

10.1016/j.tetlet.2012.12.040

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Condensations of o-halo-substituted benzenesulfonyl chlorides with 3-aminoazoles give the corresponding azolo[c][1,2,4]benzothiadiazine S,S-dioxides. o-Fluorobenzenesulfonyl chlorides and o-bromobenzene sulfonyl chlorides bearing a nitro group are reactive enough to give the desired azolo[c][1,2,4]-benzothiadiazine S,S-dioxides in a one-pot, base-promoted reaction. In all other cases, open-chain sulfonylated 3-aminoazole intermediates are isolated. The latter are converted into the title compounds upon addition of a copper(I) catalyst. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：986 / 988

页数：3

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