Stereospecific interstrand carbinolamine cross-linking by crotonaldehyde-derived 1,N2-propano-2′-deoxyguanosine DNA adducts in the 5′-CpG-3′ sequence.

被引:0
|
作者
Cho, YJ
Jacob, J
Voehler, M
Huang, H
Kim, HY
Kozekov, ID
Wang, H
Kurtz, AJ
Harris, TM
Rizzo, CJ
Lloyd, RS
Stone, MP
机构
[1] Vanderbilt Univ, Ctr Mol Toxicol, Dept Chem, Nashville, TN 37235 USA
[2] Vanderbilt Univ, Ctr Mol Toxicol, Dept Biochem, Nashville, TN 37235 USA
[3] Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37235 USA
[4] Univ Texas, Med Branch, Sealy Ctr Mol Sci, Galveston, TX 77555 USA
[5] Univ Texas, Med Branch, Dept Human Biol Chem & Genet, Galveston, TX 77555 USA
[6] Oregon Hlth Sci Univ, Ctr Res Environm & Occupat Toxicol, Portland, OR 97239 USA
关键词
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
24
引用
收藏
页码:1971 / 1971
页数:1
相关论文
共 36 条
  • [1] Stereospecific interstrand carbinolamine crosslinking by crotonalldehyde-derived 1,N2-propano-2-deoxyguanosine DNA adducts in the 5'-CpG-3' sequence
    Cho, YJ
    Jacob, J
    Voehler, M
    Huang, H
    Kim, HY
    Kozekov, ID
    Wang, H
    Kurtz, AJ
    Harris, TM
    Rizzo, CJ
    Lloyd, RS
    Stone, MP
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U1840 - U1841
  • [2] Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived α-CH3-γ-OH-1,N2-propano-2′-deoxyguanosine adducts in the 5′-CpG-3′ sequence
    Cho, YJ
    Wang, H
    Kozekov, ID
    Kurtz, AJ
    Jacob, J
    Voehler, M
    Smith, J
    Harris, TM
    Lloyd, RS
    Rizzo, CJ
    Stone, MP
    CHEMICAL RESEARCH IN TOXICOLOGY, 2006, 19 (02) : 195 - 208
  • [3] Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5′-CpG-3′ sequence by the acrolein-derived γ-OH-1,N2-propano-2′-deoxyguanosine DNA adduct
    Cho, YJ
    Kim, HY
    Huang, H
    Slutsky, A
    Minko, IG
    Wang, H
    Nechev, LV
    Kozekov, ID
    Kozekova, A
    Tamura, P
    Jacob, J
    Voehler, M
    Harris, TM
    Lloyd, RS
    Rizzo, CJ
    Stone, MP
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (50) : 17686 - 17696
  • [4] Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5′-CpG-3′ sequence by the acrolein-derived γ-OH-1,N2-propano-2′-deoxyguanosine DNA adduct
    Cho, Young-Jin
    Kim, Hye-Young
    Huang, Hai
    Slutsky, Alvira
    Minko, Irina G.
    Wang, Hao
    Nechev, Lubomir V.
    Kozekov, Ivan D.
    Kozekova, Albena
    Tamura, Pamela
    Jacob, Jaison
    Voehler, Markus
    Harris, Thomas M.
    Lloyd, R. Stephen
    Rizzo, Carmelo J.
    Stone, Michael P.
    Journal of the American Chemical Society, 2005, 127 (50): : 17686 - 17696
  • [5] Stereospecific Formation of the (R)-γ-Hydroxytrimethylene Interstrand N2-dG:N2-dG Cross-Link Arising from the γ-OH-1, N2-Propano-2′-deoxyguanosine Adduct in the 5′-CpG-3′ DNA Sequence
    Huang, Hai
    Kim, Hye-Young
    Kozekov, Ivan D.
    Cho, Young-Jin
    Wang, Hao
    Kozekova, Albena
    Harris, Thomas M.
    Rizzo, Carmelo J.
    Stone, Michael P.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (24) : 8416 - 8424
  • [6] Detection of an interchain carbinolamine cross-link formed in a CpG sequence by the acrolein DNA adduct γ-Oh-1,N2-propano-2′-deoxyguanosine
    Kim, HYH
    Voehler, M
    Harris, TM
    Stone, MP
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (32) : 9324 - 9325
  • [7] Stereochemistry modulates the stability of reduced interstrand cross-links arising from R- and S-α-CH3-γ-OH-1,N2-propano-2′-deoxyguanosine in the 5′-CpG-3′ DNA sequence
    Cho, Young-Jin
    Kozekov, Ivan D.
    Harris, Thomas M.
    Rizzo, Carmelo J.
    Stone, Michael P.
    BIOCHEMISTRY, 2007, 46 (10) : 2608 - 2621
  • [8] The Stereochemistry of trans-4-Hydroxynonenal-Derived Exocyclic 1,N2-2′-Deoxyguanosine Adducts Modulates Formation of Interstrand Cross-Links in the 5′-CpG-3′ Sequence
    Huang, Hai
    Wang, Hao
    Qi, Nan
    Lloyd, R. Stephen
    Rizzo, Carmelo J.
    Stone, Michael P.
    BIOCHEMISTRY, 2008, 47 (44) : 11457 - 11472
  • [9] Orientation of the crotonaldehyde-derived N2-[3-oxo-1(S)-methyl-propyl]-dGDNA adduct hinders interstrand cross-link formation in the 5′-CpG-3′ sequence
    Cho, Young-Jin
    Wang, Hao
    Kozekov, Ivan D.
    Kozekova, Albena
    Kurtz, Andrew J.
    Jacob, Jaison
    Voehler, Markus
    Smith, Jarrod
    Harris, Thomas M.
    Rizzo, Carmelo J.
    Lloyd, R. Stephen
    Stone, Michael P.
    CHEMICAL RESEARCH IN TOXICOLOGY, 2006, 19 (08) : 1019 - 1029
  • [10] Detection of an interchain cross-link formed in a CpG sequence by the acrolein DNA adduct γ-OH-1,N2-propano-2'-deoxyguanosine.
    Kim, HYH
    Voehler, M
    Harris, TM
    Stone, MP
    BIOCHEMISTRY, 2002, 41 (28) : 8991 - 8991