C7-Heteroaryl-indoles as potent and orally bioavailable inhibitors of HIV attachment

被引：0

作者：

Yeung, Kap-Sun ^{[1
]}

Qiu, Zhilei ^{[1
]}

Fang, Haiquan ^{[1
]}

Yin, Zhiwei ^{[1
]}

Farkas, Michelle E. ^{[1
]}

Trehan, Ashok ^{[1
]}

Pearce, Bradley ^{[1
]}

Wright, J. J. Kim ^{[1
]}

Ricandi, Keith ^{[1
]}

Spicer, Timothy P. ^{[1
]}

Shi, Pei-Yong ^{[1
]}

Gong, Yi-Fei ^{[1
]}

Colonno, Richard J. ^{[1
]}

Yang, Zheng ^{[1
]}

Zadjura, Lisa ^{[1
]}

D'Arienzo, Celia J. ^{[1
]}

Browning, Marc R. ^{[1
]}

Hansel, Steven ^{[1
]}

Santone, Kenneth ^{[1
]}

Barker, Jonathan ^{[2
]}

Taylor, Malcolm ^{[2
]}

Coxhead, Richard ^{[2
]}

Thomas, Russell ^{[2
]}

Coulter, Thomas ^{[2
]}

Lin, Ping-Fan ^{[1
]}

Meanwell, Nicholas A. ^{[1
]}

Kadow, John F. ^{[1
]}

机构：

[1] Bristol Myers Squibb R&D, Wallingford, CT 06492 USA

[2] Evotec UK Ltd, Abingdon OX14 4SA, Oxon, England

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 237卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

208-MEDI

引用

页数：1

共 50 条

[1] Inhibitors of HIV-1 attachment. Part 7: Indole-7-carboxamides as potent and orally bioavailable antiviral agents
Yeung, Kap-Sun
Qiu, Zhilei
Xue, Quifen
Fang, Haiquan
Yang, Zheng
Zadjura, Lisa
D'Arienzo, Celia J.
Eggers, Betsy J.
Riccardi, Keith
Shi, Pei-Yong
Gong, Yi-Fei
Browning, Marc R.
Gao, Qi
Hansel, Steven
Santone, Kenneth
Lin, Ping-Fang
Meanwell, Nicholas A.
Kadow, John F.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (01) : 198 - 202
[2] Tricyclic HIV integrase inhibitors: Potent and orally bioavailable C5-aza analogs
Jin, Haolun
Wright, Matthew
Pastor, Richard
Mish, Michael
Metobo, Sammy
Jabri, Salman
Lansdown, Rachael
Cai, Ruby
Pyun, Peter
Tsiang, Manuel
Chen, Xiaowu
Kim, Choung U.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (04) : 1388 - 1391
[3] DESIGN AND SYNTHESIS OF POTENT, ORALLY BIOAVAILABLE HIV-1 PROTEASE INHIBITORS
KALDOR, SW
KALISH, V
DRESSMAN, BA
FRITZ, JE
HAMMOND, M
CROWELL, TA
TATLOCK, J
REICH, S
DAVIES, J
APPELT, K
SHETTY, B
SU, KS
CAMPANALE, KM
BURGESS, JA
LUBBENHUSEN, PP
BAXTER, AJ
MUESING, MA
HATCH, SD
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 208 : 17 - MEDI
[4] Mandeloamides as potent orally bioavailable ACAT inhibitors.
Srivastava, AS
Ko, SS
Kezar, H
Tanabe, K
Frietze, WE
Billheimer, JT
Munzer, DA
Wexler, RR
Gillies, PJ
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1996, 211 : 157 - MEDI
[5] Discovery of Potent, Orally Bioavailable Inhibitors of Human Cytomegalovirus
Fader, Lee
Brault, Martine
Desjardins, Jessica
Dansereau, Nathalie
Lamorte, Louie
Tremblay, Sonia
Bilodeau, Francois
Bordeleau, Josee
Duplessis, Martin
Gorys, Vida
Gillard, James
Gleason, James L.
James, Clint
Joly, Marc-Andre
Kuhn, Cyrille
Llinas-Brunet, Montse
Luo, Laibin
Morency, Louis
Morin, Sebastien
Parisien, Mathieu
Poirier, Maude
Thibeault, Carl
Thao Trinh
Sturino, Claudio
Srivastava, Sanjay
Yoakim, Christiane
Franti, Michael
ACS MEDICINAL CHEMISTRY LETTERS, 2016, 7 (05): : 525 - 530
[6] Discovery of potent and orally bioavailable macrocyclic FXIa inhibitors
Yang, Wu
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
[7] Orally bioavailable potent soluble epoxide hydrolase inhibitors
Hwang, Sung Hee
Tsai, Hsing-Ju
Liu, Jun-Yan
Morisseau, Christophe
Hammock, Bruce D.
JOURNAL OF MEDICINAL CHEMISTRY, 2007, 50 (16) : 3825 - 3840
[8] Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus
Lu, ZJ
Bohn, J
Rano, T
Rutkowski, CA
Simcoe, AL
Olsen, DB
Schleif, WA
Carella, A
Gabryelski, L
Jin, LX
Lin, JH
Emini, E
Chapman, K
Tata, JR
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (23) : 5311 - 5314
[9] Design and synthesis of bicyclic pyrimidinones as potent and orally bioavailable HIV-1 integrase inhibitors
Muraglia, Ester
Kinzel, Olaf
Gardelli, Cristina
Crescenzi, Benedetta
Donghi, Monica
Ferrara, Marco
Nizi, Emanuela
Orvieto, Federica
Pescatore, Giovanna
Laufer, Ralph
Gonzalez-Paz, Odalys
Di Marco, Annalise
Fiore, Fabrizio
Monteagudo, Edith
Fonsi, Massimiliano
Felock, Peter J.
Rowley, Michael
Summa, Vincenzo
JOURNAL OF MEDICINAL CHEMISTRY, 2008, 51 (04) : 861 - 874
[10] Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity
Leger, Paul R.
Hu, Dennis X.
Biannic, Berenger
Bui, Minna
Han, Xinping
Karbarz, Emily
Maung, Jack
Okano, Akinori
Osipov, Maksim
Shibuya, Grant M.
Young, Kyle
Higgs, Christopher
Abraham, Betty
Bradford, Delia
Cho, Cynthia
Colas, Christophe
Jacobson, Scott
Ohol, Yamini M.
Pookot, Deepa
Rana, Payal
Sanchez, Jerick
Shah, Niket
Sun, Michael
Wong, Steve
Brockstedt, Dirk G.
Kassner, Paul D.
Schwarz, Jacob B.
Wustrow, David J.
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 63 (10) : 5398 - 5420

← 1 2 3 4 5 →