Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies

被引:318
|
作者
Muraki, Isao [1 ]
Imamura, Fumiaki [2 ]
Manson, JoAnn E. [3 ,4 ,5 ,6 ]
Hu, Frank B. [1 ,3 ,5 ,6 ]
Willett, Walter C. [1 ,3 ,5 ,6 ]
van Dam, Rob M. [1 ,7 ,8 ,9 ]
Sun, Qi [1 ,5 ,6 ]
机构
[1] Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA
[2] Univ Cambridge, Addenbrookes Hosp, Inst Metab Sci, MRC Epidemiol Unit, Cambridge CB2 2QQ, England
[3] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[4] Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA
[5] Harvard Univ, Sch Med, Boston, MA 02115 USA
[6] Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA 02115 USA
[7] Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore 117548, Singapore
[8] Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore 117595, Singapore
[9] Natl Univ Hlth Syst, Singapore, Singapore
来源
基金
美国国家卫生研究院;
关键词
CORONARY-HEART-DISEASE; DIETARY FIBER; GLYCEMIC LOAD; VEGETABLE INTAKE; RESVERATROL SUPPLEMENTATION; MEAT INTAKE; INSULIN SENSITIVITY; PHYSICAL-ACTIVITY; IN-VITRO; MELLITUS;
D O I
10.1136/bmj.f5001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective To determine whether individual fruits are differentially associated with risk of type 2 diabetes. Design Prospective longitudinal cohort study. Setting Health professionals in the United States. Participants 66 105 women from the Nurses' Health Study (1984-2008), 85 104 women from the Nurses' Health Study II (1991-2009), and 36 173 men from the Health Professionals Follow-up Study (1986-2008) who were free of major chronic diseases at baseline in these studies. Main outcome measure Incident cases of type 2 diabetes, identified through self report and confirmed by supplementary questionnaires. Results During 3 464 641 person years of follow-up, 12 198 participants developed type 2 diabetes. After adjustment for personal, lifestyle, and dietary risk factors of diabetes, the pooled hazard ratio of type 2 diabetes for every three servings/week of total whole fruit consumption was 0.98 (95% confidence interval 0.96 to 0.99). With mutual adjustment of individual fruits, the pooled hazard ratios of type 2 diabetes for every three servings/week were 0.74 (0.66 to 0.83) for blueberries, 0.88 (0.83 to 0.93) for grapes and raisins, 0.89 (0.79 to 1.01) for prunes, 0.93 (0.90 to 0.96) for apples and pears, 0.95 (0.91 to 0.98) for bananas, 0.95 (0.91 to 0.99) for grapefruit, 0.97 (0.92 to 1.02) for peaches, plums, and apricots, 0.99 (0.95 to 1.03) for oranges, 1.03 (0.96 to 1.10) for strawberries, and 1.10 (1.02 to 1.18) for cantaloupe. The pooled hazard ratio for the same increment in fruit juice consumption was 1.08 (1.05 to 1.11). The associations with risk of type 2 diabetes differed significantly among individual fruits (P<0.001 in all cohorts). Conclusion Our findings suggest the presence of heterogeneity in the associations between individual fruit consumption and risk of type 2 diabetes. Greater consumption of specific whole fruits, particularly blueberries, grapes, and apples, is significantly associated with a lower risk of type 2 diabetes, whereas greater consumption of fruit juice is associated with a higher risk.
引用
收藏
页数:15
相关论文
共 50 条
  • [1] Potato Consumption and Risk of Type 2 Diabetes: Results From Three Prospective Cohort Studies
    Muraki, Isao
    Rimm, Eric B.
    Willett, Walter C.
    Manson, JoAnn E.
    Hu, Frank B.
    Sun, Qi
    [J]. DIABETES CARE, 2016, 39 (03) : 376 - 384
  • [2] Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies (vol 347, f5001, 2013)
    Muraki, Isao
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2013, 347
  • [3] Ultra-processed food consumption and risk of type 2 diabetes: results from three prospective cohort studies in the US
    Chen, Z.
    Khandpur, N.
    Monteiro, C.
    Rossato, S.
    Fung, T.
    Manson, J. E.
    Willett, W.
    Rimm, E. B.
    Hu, F. B.
    Sun, Q.
    Drouin-Chartier, J. -P.
    [J]. DIABETOLOGIA, 2022, 65 (SUPPL 1) : S3 - S4
  • [4] Cooking Methods for Meats and Risk of Type 2 Diabetes: Results From Three Prospective Cohort Studies
    Liu, Gang
    Zong, Geng
    Hu, Yang
    Hu, Frank B.
    Willett, Walter C.
    Eisenberg, David
    Sun, Qi
    [J]. CIRCULATION, 2017, 135
  • [5] Intake of Chocolate by Subtypes and Risk of Type 2 Diabetes: Results From Three Prospective Cohort Studies
    Liu, Binkai
    Zhu, Lu
    Hu, Yang
    Manson, Joann E.
    Sun, Qi
    [J]. CIRCULATION, 2023, 147
  • [6] Meat Cooking Methods and Risk of Type 2 Diabetes: Results From Three Prospective Cohort Studies
    Liu, Gang
    Zong, Geng
    Wu, Kana
    Hu, Yang
    Li, Yanping
    Willett, Walter C.
    Eisenberg, David M.
    Hu, Frank B.
    Sun, Qi
    [J]. DIABETES CARE, 2018, 41 (05) : 1049 - 1060
  • [7] Intake of whole grain foods and risk of type 2 diabetes: results from three prospective cohort studies
    Hu, Yang
    Ding, Ming
    Sampson, Laura
    Willett, Walter C.
    Manson, JoAnn E.
    Wang, Molin
    Rosner, Bernard
    B. Hu, Frank
    Sun, Qi
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2020, 370
  • [8] Dietary Inflammatory and Insulinemic Potential and Risk of Type 2 Diabetes: Results From Three Prospective US Cohort Studies
    Lee, Dong Hoon
    Li, Jun
    Li, Yanping
    Liu, Gang
    Wu, Kana
    Bhupathiraju, Shilpa
    Rimm, Eric B.
    Rexrode, Kathryn M.
    Manson, JoAnn E.
    Willett, Walter C.
    Hu, Frank B.
    Tabung, Fred K.
    Giovannucci, Edward L.
    [J]. DIABETES CARE, 2020, 43 (11) : 2675 - 2683
  • [9] Regular use of proton pump inhibitors and risk of type 2 diabetes: results from three prospective cohort studies
    Yuan, Jinqiu
    He, Qiangsheng
    Nguyen, Long H.
    Wong, Martin C. S.
    Huang, Junjie
    Yu, Yuanyuan
    Xia, Bin
    Tang, Yan
    He, Yulong
    Zhang, Changhua
    [J]. GUT, 2021, 70 (06) : 1070 - 1077
  • [10] Age at Menarche and Risk of Type 2 Diabetes: Results From 2 Large Prospective Cohort Studies
    He, Chunyan
    Zhang, Cuilin
    Hunter, David J.
    Hankinson, Susan E.
    Louis, Germaine M. Buck
    Hediger, Mary L.
    Hu, Frank B.
    [J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 2010, 171 (03) : 334 - 344