Inside Anesthesia Breathing Circuits: Time to Reach a Set Sevoflurane Concentration in Toddlers and Newborns: Simulation Using a Test Lung

被引：6

作者：

Kern, Delphine ^{[1
]}

Larcher, Claire ^{[1
]}

Basset, Bertrand ^{[1
]}

Alacoque, Xavier ^{[1
]}

Fesseau, Rose ^{[1
]}

Samii, Kamran ^{[1
]}

Minville, Vincent ^{[1
]}

Fourcade, Olivier ^{[1
]}

机构：

[1] Univ Hosp Toulouse, Dept Anesthesiol & Intens Care, EA MATN 4564, CHRU Toulouse Purpan,IFR 150, F-31059 Toulouse 9, France

来源：

ANESTHESIA AND ANALGESIA | 2012年 / 115卷 / 02期

关键词：

PEDIATRIC ANESTHESIA; LARYNGOSPASM; DELIVERY; MACHINE; VENTILATORS; SYSTEMS;

D O I：

10.1213/ANE.0b013e318257570f

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We measured the time it takes to reach the desired inspired anesthetic concentration using the Primus (Dragerwerk, AG, Lubeck, Germany) and the Avance (GE Datex-Ohmeda, Munich, Germany) anesthesia machines with toddler and newborn ventilation settings. The time to reach 95% of inspired target sevoflurane concentration was measured during wash-in from 0 to 6 vol% sevoflurane and during wash-out from 6 to 0 vol% with fresh gas flows equal to 1 and 2 times the minute ventilation. The Avance was faster than the Primus (65 seconds [95% confidence interval (CI): 55 to 78] vs 310 seconds [95% CI: 261 to 359]) at 1.5 L/min fresh gas flow, tidal volume of 50 mL, and 30 breaths/min. Times were shorter by the same magnitude at higher fresh gas flows and higher minute ventilation rates. The effect of doubling fresh gas flow was variable and less than expected. The Primus is slower during newborn than toddler ventilation, whereas the Avance's response time was the same for newborn and toddler ventilation. Our data confirm that the time to reach the target-inspired anesthetic concentration depends on breathing circuit volume, fresh gas flow, and minute ventilation. (Anesth Analg 2012;115:310-4)

引用

页码：310 / 314

页数：5