Synthesis of secondary propargyl alcohols from aromatic and heteroaromatic aldehydes and acetylene in the system KOH-H2O-DMSO

被引：19
|
作者：
Sobenina, L. N. [1 ]
Tomilin, D. N. [1 ]
Petrova, O. V. [1 ]
Mikhaleva, A. I. [1 ]
Trofimov, B. A. [1 ]
机构：
[1] Russian Acad Sci, Siberian Branch, Favorskii Irkutsk Inst Chem, Irkutsk 664033, Russia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 49卷 / 03期
关键词：
IN-SITU GENERATION; TERMINAL ALKYNES; ALLYLIC ALCOHOLS; OXIDATION; PYRIDINES; REAGENT; FACILE;
D O I：
10.1134/S107042801303007X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Ethynylation of aromatic and heteroaromatic aldehydes with acetylene under atmospheric pressure in the catalytic system KOH-H2O-DMSO (aldehyde-KOH molar ratio 1 : 2, -5 to -7A degrees C, 3 h) gave secondary propargyl alcohols in 46-67% yield.
引用
收藏
页码：356 / 359
页数：4
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