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- [1] QSAR studies on imidazopyrazine derivatives as Aurora A kinase inhibitorsSAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2012, 23 (7-8) : 705 - 730Leng, Y.论文数: 0 引用数: 0 h-index: 0机构: China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R China China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R ChinaLu, T.论文数: 0 引用数: 0 h-index: 0机构: China Pharmaceut Univ, State Key Lab Nat Med, Nanjing, Jiangsu, Peoples R China China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R ChinaYuan, H. L.论文数: 0 引用数: 0 h-index: 0机构: China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R China China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R ChinaLiu, H. C.论文数: 0 引用数: 0 h-index: 0机构: China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R China China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R ChinaLu, S.论文数: 0 引用数: 0 h-index: 0机构: China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R China China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R ChinaZhang, W. W.论文数: 0 引用数: 0 h-index: 0机构: China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R China China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R ChinaJiang, Y. L.论文数: 0 引用数: 0 h-index: 0机构: China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R China China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R ChinaChen, Y. D.论文数: 0 引用数: 0 h-index: 0机构: China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R China China Pharmaceut Univ, State Key Lab Nat Med, Nanjing, Jiangsu, Peoples R China China Pharmaceut Univ, Sch Basic Sci, Lab Mol Design & Drug Discovery, Nanjing, Jiangsu, Peoples R China
- [2] Synthesis and characterization of imidazopyrazine derivatives as VAV1 inhibitorsABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256Gerspacher, Marc论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandSkaanderup, Philip论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandImbach-Weese, Patricia论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandMetoul, Lionel Doumampouom论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandRoehn-Carnemolla, Esther论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandArz, Dorothee论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandGarlot, Audrey-Laure论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandRemond, Anne-Catherine论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandEric, Vangrevelinghe论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandKnapp, Mark论文数: 0 引用数: 0 h-index: 0机构: Novartis Inst BioMed Res, Emeryville, CA USA Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandLingel, Andreas论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandStucke, Volker论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandChene, Patrick论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, SwitzerlandHofmann, Francesco论文数: 0 引用数: 0 h-index: 0机构: Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland Novartis Pharma AG, Novartis Inst BioMed Res Basel, Basel, Switzerland
- [3] Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric InhibitorsACS MEDICINAL CHEMISTRY LETTERS, 2023, 14 (02): : 156 - 162Torrente, Esther论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyFodale, Valentina论文数: 0 引用数: 0 h-index: 0机构: Dept Biol & Translat Res, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyCiammaichella, Alina论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyFerrigno, Federica论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyOntoria, Jesus M.论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyPonzi, Simona论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyRossetti, Ilaria论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalySferrazza, Alessio论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyAmaudrut, Jerome论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyMissineo, Antonino论文数: 0 引用数: 0 h-index: 0机构: Dept Biol & Translat Res, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyEsposito, Simone论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyPalombo, Simone论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyNibbio, Martina论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyCerretani, Mauro论文数: 0 引用数: 0 h-index: 0机构: Dept Biol & Translat Res, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyBisbocci, Monica论文数: 0 引用数: 0 h-index: 0机构: Dept Biol & Translat Res, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyCellucci, Antonella论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, Italydi Marco, Annalise论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyAlli, Cristina论文数: 0 引用数: 0 h-index: 0机构: Dept Biol & Translat Res, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyPucci, Vincenzo论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyToniatti, Carlo论文数: 0 引用数: 0 h-index: 0机构: Dept Biol & Translat Res, I-00071 Rome, Italy Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, ItalyPetrocchi, Alessia论文数: 0 引用数: 0 h-index: 0机构: Dept Drug Discovery IRBM SpA, I-00071 Rome, Italy Dept Biol & Translat Res, I-00071 Rome, Italy
- [4] Benzofuran derivatives as anticancer inhibitors of mTOR signalingEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 81 : 181 - 191Salome, Christophe论文数: 0 引用数: 0 h-index: 0机构: Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, France Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, FranceRibeiro, Nigel论文数: 0 引用数: 0 h-index: 0机构: Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, France Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, FranceChavagnan, Thierry论文数: 0 引用数: 0 h-index: 0机构: Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, France Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, FranceThuaud, Frederic论文数: 0 引用数: 0 h-index: 0机构: Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, France Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, FranceSerova, Maria论文数: 0 引用数: 0 h-index: 0机构: AAREC Filia Res, F-92100 Boulogne, France Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, Francede Gramont, Armand论文数: 0 引用数: 0 h-index: 0机构: AAREC Filia Res, F-92100 Boulogne, France Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, FranceFaivre, Sandrine论文数: 0 引用数: 0 h-index: 0机构: Beaujon Univ Hosp, AP HP, INSERM U728, Dept Med Oncol, Clichy, France Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, FranceRaymond, Eric论文数: 0 引用数: 0 h-index: 0机构: Beaujon Univ Hosp, AP HP, INSERM U728, Dept Med Oncol, Clichy, France Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, FranceDesaubry, Laurent论文数: 0 引用数: 0 h-index: 0机构: Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, France Univ Strasbourg, UMR7200, Therapeut Innovat Lab, CNRS, Illkirch Graffenstaden, France
- [5] Benzofuran derivatives as a novel class of mTOR signaling inhibitorsCANCER RESEARCH, 2014, 74 (19)Serova, Marie论文数: 0 引用数: 0 h-index: 0机构: AAREC Filia Res, Clichy, France INSERM U728, Clichy, France AAREC Filia Res, Clichy, FranceSalome, Christophe论文数: 0 引用数: 0 h-index: 0机构: CNRS Univ Strasbourg, UMR7200, Illkirch Graffenstaden, France AAREC Filia Res, Clichy, FranceNarbonne, Vanessa论文数: 0 引用数: 0 h-index: 0机构: CNRS Univ Strasbourg, UMR7200, Illkirch Graffenstaden, France AAREC Filia Res, Clichy, FranceRibeiro, Nigel论文数: 0 引用数: 0 h-index: 0机构: CNRS Univ Strasbourg, UMR7200, Illkirch Graffenstaden, France AAREC Filia Res, Clichy, FranceThuaud, Frederic论文数: 0 引用数: 0 h-index: 0机构: CNRS Univ Strasbourg, UMR7200, Illkirch Graffenstaden, France AAREC Filia Res, Clichy, FranceRaymond, Eric论文数: 0 引用数: 0 h-index: 0机构: Beaujon Univ Hosp, INSERM U728, Clichy, France Beaujon Univ Hosp, Dept Med Oncol, Clichy, France AAREC Filia Res, Clichy, Francede Gramont, Armand论文数: 0 引用数: 0 h-index: 0机构: AAREC Filia Res, Clichy, France INSERM U728, Clichy, France AAREC Filia Res, Clichy, FranceDesaubry, Laurent论文数: 0 引用数: 0 h-index: 0机构: CNRS Univ Strasbourg, UMR7200, Illkirch Graffenstaden, France AAREC Filia Res, Clichy, France
- [6] Benzofuran derivatives as a novel class of inhibitors of mTOR signalingEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 74 : 41 - 49Salome, Christophe论文数: 0 引用数: 0 h-index: 0机构: Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, France Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, FranceNarbonne, Vanessa论文数: 0 引用数: 0 h-index: 0机构: Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, France Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, FranceRibeiro, Nigel论文数: 0 引用数: 0 h-index: 0机构: Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, France Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, FranceThuaud, Frederic论文数: 0 引用数: 0 h-index: 0机构: Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, France Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, FranceSerova, Maria论文数: 0 引用数: 0 h-index: 0机构: Beaujon Univ Hosp, AP HP, INSERM, Dept Med Oncol,U728, Clichy, France Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, Francede Gramont, Armand论文数: 0 引用数: 0 h-index: 0机构: Beaujon Univ Hosp, AP HP, INSERM, Dept Med Oncol,U728, Clichy, France Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, FranceFaivre, Sandrine论文数: 0 引用数: 0 h-index: 0机构: Beaujon Univ Hosp, AP HP, INSERM, Dept Med Oncol,U728, Clichy, France Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, FranceRaymond, Eric论文数: 0 引用数: 0 h-index: 0机构: Beaujon Univ Hosp, AP HP, INSERM, Dept Med Oncol,U728, Clichy, France Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, FranceDesaubry, Laurent论文数: 0 引用数: 0 h-index: 0机构: Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, France Univ Strasbourg, CNRS, Therapeut Innovat Lab, Illkirch Graffenstaden, France
- [7] Novel pyrazolopyrimidine derivatives as potent mTOR kinase inhibitors with anticancer activitiesEJC SUPPLEMENTS, 2010, 8 (07): : 54 - 54Chen, S.论文数: 0 引用数: 0 h-index: 0机构: Shanghai Inst Mat Med, Div Antitumor Pharmacol, Shanghai, Peoples R China Shanghai Inst Mat Med, Div Antitumor Pharmacol, Shanghai, Peoples R ChinaMeng, L.论文数: 0 引用数: 0 h-index: 0机构: Shanghai Inst Mat Med, Div Antitumor Pharmacol, Shanghai, Peoples R China Shanghai Inst Mat Med, Div Antitumor Pharmacol, Shanghai, Peoples R ChinaLiang, C.论文数: 0 引用数: 0 h-index: 0机构: Xcovery LLC, Drug Discovery, W Palm Beach, FL USA Shanghai Inst Mat Med, Div Antitumor Pharmacol, Shanghai, Peoples R ChinaDing, J.论文数: 0 引用数: 0 h-index: 0机构: Shanghai Inst Mat Med, Div Antitumor Pharmacol, Shanghai, Peoples R China Shanghai Inst Mat Med, Div Antitumor Pharmacol, Shanghai, Peoples R China
- [8] MTOR INHIBITORSANNALS OF ONCOLOGY, 2009, 20 : 26 - 26Tabernero, J. M.论文数: 0 引用数: 0 h-index: 0机构: Vall dhebron Univ Hosp, Barcelona, Spain Vall dhebron Univ Hosp, Barcelona, Spain
- [9] mTOR inhibitorsNATURE REVIEWS DRUG DISCOVERY, 2006, 5 (08) : 625 - 625不详论文数: 0 引用数: 0 h-index: 0
- [10] Inhibitors of mTORONCOLOGIST, 2010, 15 (12): : 1262 - 1269Klumpen, Heinz-Josef论文数: 0 引用数: 0 h-index: 0机构: Univ Amsterdam, Acad Med Ctr, Dept Med Oncol, NL-1105 AZ Amsterdam, Netherlands Univ Amsterdam, Acad Med Ctr, Dept Med Oncol, NL-1105 AZ Amsterdam, NetherlandsBeijnen, Jos H.论文数: 0 引用数: 0 h-index: 0机构: Univ Utrecht, Fac Sci, Dept Pharmaceut Sci, Sect Biomed Anal,Div Drug Toxicol, Utrecht, Netherlands Slotervaart Hosp, Dept Pharm & Pharmacol, Amsterdam, Netherlands Univ Amsterdam, Acad Med Ctr, Dept Med Oncol, NL-1105 AZ Amsterdam, NetherlandsGurney, Howard论文数: 0 引用数: 0 h-index: 0机构: Univ Sydney, Westmead Hosp, Dept Med Oncol, Sydney W Area Hlth Serv, Westmead, NSW 2145, Australia Univ Amsterdam, Acad Med Ctr, Dept Med Oncol, NL-1105 AZ Amsterdam, NetherlandsSchellens, Jan H. M.论文数: 0 引用数: 0 h-index: 0机构: Netherlands Canc Inst, Dept Med Oncol, Div Clin Pharmacol, Amsterdam, Netherlands Univ Utrecht, Fac Sci, Dept Pharmaceut Sci, Sect Biomed Anal,Div Drug Toxicol, Utrecht, Netherlands Univ Amsterdam, Acad Med Ctr, Dept Med Oncol, NL-1105 AZ Amsterdam, Netherlands