Genetics of neural development in zebrafish

被引：20
|
作者：
Schier, AF
机构：
[1] Developmental Genetics Program, Skirball Intitute Biomol. Med., N., New York
来源：
CURRENT OPINION IN NEUROBIOLOGY | 1997年 / 7卷 / 01期
关键词：
D O I：
10.1016/S0959-4388(97)80129-8
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Large-scale mutant screens in zebrafish have led to the identification of more than 50 genes affecting various aspects of neural development and function, including neural induction, anteroposterior and dorsoventral regionalization, axon pathfinding, neuronal differentiation and survival, and behavior. Phenotypic analysis of mutants for some of these genes has already uncovered important genetic and cellular interactions during development. Ongoing molecular analyses promise to further elucidate the mechanisms underlying neural development in vertebrates.
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页码：119 / 126
页数：8
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