Line-field confocal optical coherence tomography

被引:7
|
作者
Ogien, Jonas [1 ]
Levecq, Olivier [1 ]
Azimani, Hicham [1 ]
Davis, Arthur [1 ,2 ]
Xue, Weikai [2 ]
Siret, David [1 ]
Perrot, Jean-Luc [3 ]
Dubois, Arnaud [2 ]
机构
[1] DAMAE Med, 28 Rue Turbigo, F-75003 Paris, France
[2] Univ Paris Sud, Grad Sch, Inst Opt, Lab Charles Fabry, F-91127 Palaiseau, France
[3] CHU St Etienne, Serv Dermatol, F-42055 St Etienne, France
关键词
Optical coherence tomography; medical and biological imaging; interference microscopy; SYNTHETIC-APERTURE; RESOLUTION; DEPTH; SCATTERING; MICROSCOPY; RANGE; OCT;
D O I
10.1117/12.2507244
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
We present an improved time-domain optical coherence tomography technique designed for ultrahigh-resolution B-scan imaging in real-time. The technique, called line-field confocal optical coherence tomography, is based on a Linnik-type interference microscope with line illumination using a supercontinuum laser and line detection using a line-scan camera. B-scan imaging with dynamic focusing is achieved by acquiring multiple A-scans in parallel. In vivo cellular level resolution imaging of skin is demonstrated at 10 frame/s with a penetration depth of similar to 500 mu m, with a spatial resolution of 1.3 mu m x 1.1 mu m (transverse x axial).
引用
收藏
页数:4
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