The impact of obesity on the cellular and molecular pathophysiology of COVID-19

被引：0
|
作者：
Dhanraj, P. [1 ]
Pitere, R. [1 ]
Pepper, M. S. [1 ]
机构：
[1] Univ Pretoria, SAMRC Extramural Unit Stem Cell Res & Therapy, Inst Cellular & Mol Med, Dept Immunol,Fac Hlth Sci, Pretoria, South Africa
来源：
SAMJ SOUTH AFRICAN MEDICAL JOURNAL | 2021年 / 111卷 / 03期
基金：
英国医学研究理事会; 新加坡国家研究基金会;
关键词：
CYTOKINE STORM; HOSPITALIZED-PATIENTS; CHRONIC INFLAMMATION; IMMUNE-RESPONSE; DISEASES; RISK; CORONAVIRUS; CONSEQUENCES; PATHOGENESIS; PROTEIN;
D O I：
10.7196/SAMJ.2021.v111i3.15398
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Emerging evidence reveals a strong association between COVID-19 and obesity in terms of disease severity, need for hospitalisation and risk of mortality. In this review, we discuss cellular and molecular mechanisms potentially contributing to the pathophysiology of COVID-19 in obese patients. Understanding the relationship between COVID-19 and obesity is pertinent for the clinical management of these patients.
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页码：211 / 214
页数：4
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