New therapeutics for hereditary angioedema - unanswered questions in hereditary angioedema

New therapeutics for hereditary angioedema - unanswered questions in hereditary angio edema Hereditary angioedema (HAE) is a rare disease with an estimated prevalence of 1:50,000. Some time around the year 2000, scientific interest in HAE started to rise. The developments resulting from this interest led to an improvement in patient's care. The number of drugs licensed for HAE treatment have multiplied, others are currently tested in clinical studies. This article describes the most important changes and developments of the recent years and focuses on known and new open questions in the field of RAE research.