Induction Therapy with "3+7" Chemotherapy Plus ATRA Followed by Consolidations with Three Courses of Idarubicin Alone and Maintenance Therapy with ATRA in Newly Diagnosed Acute Promyelocytic Leukemia (APL) Has An Excellent Leukemia-Free Survival but Minimal Toxicity in Low and Intermediate Risk Groups

被引：0

作者：

Choi, Moon-Young ^{[1
]}

Mun, Yeung-Chul ^{[1
]}

Park, Se Hoon ^{[2
]}

Cho, Eun Kyung ^{[2
]}

Lee, Jae Hoon ^{[2
]}

Jo, Deog Yeon ^{[3
]}

Kim, Inho ^{[4
]}

Bang, Soo-Mee ^{[4
]}

Yoon, Sung-Soo ^{[4
]}

Park, Seonyang ^{[4
]}

Kim, Byoung Kook ^{[4
]}

Kim, Hawk ^{[5
]}

Min, Young Joo ^{[5
]}

Park, Jae Hoo ^{[5
]}

Seo, Jong Jin ^{[5
]}

Moon, Hyung Nam ^{[5
]}

Lee, Moon Hee ^{[6
]}

Kim, Cheol Soo ^{[7
]}

Lee, Won Sik ^{[8
]}

Joo, Young Don ^{[8
]}

Chung, So Young ^{[9
]}

Oh, Doyeun ^{[9
]}

Zang, Dae Young ^{[10
]}

Lee, Kyung Hee ^{[11
]}

Hyun, Myung Soo ^{[11
]}

Song, Hong Suk ^{[12
]}

Kim, Heung Sik ^{[12
]}

Kim, Sung Hyun ^{[13
]}

Kwon, Hyuk Chan ^{[13
]}

Kim, Hyo Jin ^{[13
]}

Park, Kyung Tae ^{[14
]}

Ahn, Jin Seok ^{[15
]}

Park, Yeon Hee ^{[15
]}

Ahn, Myung Ju ^{[15
]}

Bae, Sung Hwa ^{[16
]}

Ryoo, Hun-Mo ^{[16
]}

Choi, Jung-Hye ^{[18
]}

Yoon, Hwi-Joong ^{[17
]}

Nam, Seung-Hyun ^{[19
]}

Kim, Bong-Seog ^{[19
]}

Ghim, Thad T. ^{[20
]}

Seong, Chu-Myong ^{[1
]}

机构：

[1] Ewha Womans Univ, Sch Med, Seoul, South Korea

[2] Gachon Univ Med & Sci, Inchon, South Korea

[3] Chungnam Natl Univ, Coll Med, Taejon, South Korea

[4] Seoul Natl Univ, Coll Med, Seoul, South Korea

[5] Univ Ulsan, Coll Med, Ulsan 680749, South Korea

[6] Inha Univ, Sch Med, Dept Internal Med, Inchon, South Korea

[7] Inha Univ, Coll Med, Inchon, South Korea

[8] Inje Univ, Coll Med, Pusan, South Korea

[9] Pochon CHA Univ, Coll Med, Songnam, South Korea

[10] Hallym Univ, Coll Med, Anyang, South Korea

[11] Yeungnam Univ, Coll Med, Taegu, South Korea

[12] Kyemyung Univ, Coll Med, Taegu, South Korea

[13] Dong A Univ, Coll Med, Pusan, South Korea

[14] Sungkyunkwan Univ, Sch Med, Masan, South Korea

[15] Sungkyunkwan Univ, Sch Med, Seoul, South Korea

[16] Daegu Catholic Univ, Sch Med, Taegu, South Korea

[17] Kyung Hee Univ, Coll Med, Seoul, South Korea

[18] Hanyang Univ, Coll Med, Seoul, South Korea

[19] Seoul Vet Hosp, Seoul, South Korea

[20] Korea Natl Canc Ctr, Goyang, South Korea

来源：

BLOOD | 2009年 / 114卷 / 22期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：817 / 818

页数：2

共 5 条

[1] INDUCTION THERAPY WITH '3+7'CHEMOTHERAPY PLUS ATRA FOLLOWED BY CONSOLIDATIONS WITH THREE COURSES OF IDARUBICIN ALONE AND MAINTENANCE THERAPY WITH ATRA IN NEWLY DIAGNOSED ACUTE PROMYELOCYTIC LEUKEMIA HAS AN EXCELLENT LEUKEMIA-FREE SURVIVAL BUT MINIMAL TOXICITY IN LOW AND INTERMEDIATE RISK GROU
Mun, Y. C.
Choi, M. Y.
Cho, E. K.
Lee, J. H.
Jo, D. Y.
Kim, I. H.
Bang, S. M.
Yoon, S. S.
Park, S. Y.
Kim, B. K.
Kim, H.
Min, Y. J.
Park, J. H.
Seo, J. J.
Moon, H. N.
Lee, M. H.
Kim, C. S.
Lee, W. S.
Joo, Y. D.
Chung, S. Y.
Oh, D. Y.
Zang, D. Y.
Lee, K. H.
Hyun, M. S.
Song, H. S.
Kim, H. S.
Kim, S. H.
Kwon, H. C.
Kim, H. J.
Ahn, M. J.
Ahn, J. S.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 : 123 - 123
[2] A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia
Fenaux, P
Chastang, C
Chevret, S
Sanz, M
Dombret, H
Archimbaud, E
Fey, M
Rayon, C
Huguet, F
Sotto, JJ
Gardin, C
Makhoul, PC
Travade, P
Solary, E
Fegueux, N
Bordessoule, D
San Miguel, J
Link, H
Desablens, B
Stamatoullas, A
Deconinck, E
Maloisel, F
Castaigne, S
Preudhomme, C
Degos, L
BLOOD, 1999, 94 (04) : 1192 - 1200
[3] ATRA followed by chemotherapy (CT) vs ATRA plus CT and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia (APL): First interim results of APL 93 trial.
Fenaux, P
Chastang, C
Sanz, M
Thomas, X
Dombret, H
Link, H
Guerci, A
Fegueux, N
SanMiguel, J
Rayon, C
Zittoun, R
Gardin, C
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Travade, P
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Lefrere, F
Hayat, M
Castaigne, S
Chomienne, C
Degos, L
BLOOD, 1997, 90 (10) : 533 - 533
[4] ATRA followed by chemotherapy (CT) vs ATRA plus CT, and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia (APL): Long term follow up of APL 93 trial.
Fenaux, P
Chevret, S
Sanz, M
Thomas, X
Dombret, H
Rey, M
Rayon, C
Huguet, F
Sotto, JJ
Gardin, C
Cony-Makhoul, P
Travade, P
Solary, E
Fegueux, N
Bordessoule, D
San Miguel, J
Link, H
Desablens, B
Stamatoullas, A
Deconinck, E
Hess, U
Maloisel, F
Castaigne, S
Preudhomme, C
Chomienne, C
Degos, L
BLOOD, 2001, 98 (11) : 766A - 766A
[5] Induction therapy with idarubicin alone significantly influences event-free survival duration in patients with newly diagnosed hypergranular acute promyelocytic leukemia: final results of the GIMEMA randomized study LAP 0389 with 7 years of minimal follow-up
Avvisati, G
Petti, MC
Lo-Coco, F
Vegna, ML
Amadori, S
Baccarani, M
Cantore, N
Di Bona, E
Ferrara, F
Fioritoni, G
Gallo, E
Invernizzi, R
Lazzarino, M
Liso, V
Mariani, G
Ricciuti, F
Selleri, C
Sica, S
Veneri, D
Mandelli, F
BLOOD, 2002, 100 (09) : 3141 - 3146

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