piezoelectric immunosensor;
oriented immobilization of antibody;
complement C-1q;
D O I:
暂无
中图分类号:
O65 [分析化学];
学科分类号:
070302 ;
081704 ;
摘要:
A reusable piezoelectric immunosensor has been developed for the detection of human complement C-1q. Three methods for immobilization of anti-C-1q antibody on the gold electrodes were employed. The protein A method gave the best results in terms of sensitivity, stability and reproducibility. With the protein A method, the coated crystal had a good response in relevant concentration range. The electrodes could be reused 4 times by desorption of the immunocomplex with 0.1 mol/L citrate buffer.