Molecular genetics of extranodal marginal zone (MALT-type) B-cell lymphoma

被引：12
|
作者：
Bertoni, F [1 ]
Cotter, FE [1 ]
Zucca, E [1 ]
机构：
[1] Osped San Giovanni Bellinzona, Serv Oncol Cantonale, CH-6500 Bellinzona, Switzerland
来源：
LEUKEMIA & LYMPHOMA | 1999年 / 35卷 / 1-2期
基金：
美国国家科学基金会;
关键词：
molecular biology; marginal zone lymphoma; MALT; extranodal lymphoma; gastric; PCR;
D O I：
10.3109/10428199909145705
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Mucosa-associated lymphoid tissue lymphoma is now classified as extranodal marginal zone B-cell lymphoma. We reviewed the current literature on the biological and genetic mechanisms that lead to the development and progression of this unusual lymphoma. Particular attention was given to the clinical and biological significance of the immunoglobulin genes rearrangement, that has been proposed and widely used both diagnostically and as a tool to monitor the response to antibiotic treatment.
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页码：57 / 68
页数：12
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