Neural-immune system interactions in Xenopus

被引:4
|
作者
Kinney, Kevin S. [1 ]
Cohen, Nicholas [2 ]
机构
[1] Depauw Univ, Dept Biol, Greencastle, IN 46135 USA
[2] Univ Rochester, Med Ctr, Dept Microbiol & Immunol, Rochester, NY 14642 USA
来源
关键词
Amphibian; Psychoneuroimmunology; Endocrine; Neural-Immune Interactions; Comparative; Sympathetic Nervous System; Stress; NORADRENERGIC SYMPATHETIC INNERVATION; ANTIMICROBIAL PEPTIDE DEFENSES; CELL ANTIGEN-BINDING; BETA(2)-ADRENERGIC RECEPTOR; NERVOUS-SYSTEM; IN-VITRO; B-CELL; T-CELL; ANTIBODY-PRODUCTION; LYMPHOID ORGANS;
D O I
10.2741/3233
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In Xenopus, as in mammals, there is a functionally significant bidirectional communication between the neuroendocrine and immune systems. In this review, we describe the evidence for the neural innervation of Xenopus lymphoid organs, review the effects of neurotransmitter and hormone manipulations on measures of immunity, and discuss the role of hormones on immunological changes during metamorphosis. We also speculate as to the phylogenetic significance of these data, and outline possible areas of future research
引用
收藏
页码:112 / 129
页数:18
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