We study the Lagrangian velocity and acceleration statistics of light particles (micro-bubbles in water) in homogeneous isotropic turbulence. Micro-bubbles with a diameter d(b) = 340 mu m and Stokes number from 0.02 to 0.09 are dispersed in a turbulent water tunnel operated at Taylor-Reynolds numbers (Re-lambda) ranging from 160 to 265. We reconstruct the bubble trajectories by employing three-dimensional particle tracking velocimetry. It is found that the probability density functions (PDFs) of the micro-bubble acceleration show a highly non-Gaussian behavior with flatness values in the range 23 to 30. The acceleration flatness values show an increasing trend with Re-lambda, consistent with previous experiments [G. Voth, A. La Porta, A. M. Crawford, J. Alexander, and E. Bodenschatz, "Measurement of particle accelerations in fully developed turbulence," J. Fluid Mech. 469, 121 (2002)] and numerics [T. Ishihara, Y. Kaneda, M. Yokokawa, K. Itakura, and A. Uno, "Small-scale statistics in highresolution direct numerical simulation of turbulence: Reynolds number dependence of one-point velocity gradient statistics," J. Fluid Mech. 592, 335 (2007)]. These acceleration PDFs show a higher intermittency compared to tracers [S. Ayyalasomayajula, Z. Warhaft, and L. R. Collins, "Modeling inertial particle acceleration statistics in isotropic turbulence," Phys. Fluids. 20, 095104 (2008)] and heavy particles [S. Ayyalasomayajula, A. Gylfason, L. R. Collins, E. Bodenschatz, and Z. Warhaft, "Lagrangian measurements of inertial particle accelerations in grid generated wind tunnel turbulence," Phys. Rev. Lett. 97, 144507 (2006)] in wind tunnel experiments. In addition, the micro-bubble acceleration autocorrelation function decorrelates slower with increasing Re-lambda. We also compare our results with experiments in von Kaacutermaacuten flows and point-particle direct numerical simulations with periodic boundary conditions. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4719148]