Acute Necrotizing Encephalopathy of Childhood with H1N1 Infection

被引:6
|
作者
Takia, Lalit [1 ]
Patra, Nilamani [1 ]
Nallasamy, Karthi [1 ]
Saini, Lokesh [2 ]
Suthar, Renu [2 ]
Angurana, Suresh K. [1 ]
Jayashree, Muralidharan [1 ]
机构
[1] Postgrad Inst Med Educ & Res, Adv Pediat Ctr, Dept Pediat, Div Pediat Crit Care, Chandigarh, India
[2] Postgrad Inst Med Educ & Res, Adv Pediat Ctr, Dept Pediat, Div Pediat Neurol, Chandigarh, India
关键词
encephalopathy; H1N1; influenza; raised ICP; RANBP2; MUTATION; NEUROLOGIC MANIFESTATIONS; COMPLICATIONS; ENCEPHALITIS; CHILDREN;
D O I
10.1055/s-0040-1705182
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Acute necrotizing encephalopathy of childhood (ANEC) is an uncommon and fulminant complication of seasonal influenza infection associated with high mortality and poor neurological outcome. We report a 4.5-year-old female who had pneumonia, ANEC, and raised intracranial pressure (ICP) with polymerase chain reaction proven H1N1 infection. Management included mechanical ventilation, invasive monitoring and control of ICP, oseltamivir, methylprednisolone, and supportive care in pediatric intensive care unit. She survived with poor neurological status at discharge.
引用
收藏
页码:222 / 224
页数:3
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