Oncogenic Mutational Disruption of KLHL6 Dimers Fuels B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma

被引：0
|
作者：
Meriranta, Leo [1 ]
Sorri, Selma [2 ]
Zafar, Sadia [2 ]
Liu, Xiaonan [3 ]
Sahlberg, Eerika [4 ]
Dufva, Olli [5 ]
Goos, Helka [3 ]
Karjalainen-Lindsberg, Marja-Liisa [6 ]
Varjosalo, Markku [3 ]
Hyytiainen, Marko [2 ]
Leppa, Sirpa [1 ,7 ]
机构：
[1] Univ Helsinki, Fac Med, Res Programs Unit, Appl Tumor Genom, Helsinki, Finland
[2] Univ Helsinki, Res Programs Unit, Appl Tumor Genom, Helsinki, Finland
[3] Univ Helsinki, Prote Unit, HiLIFE, Inst Biotechnol, Helsinki, Finland
[4] Univ Helsinki, Fac Med, Helsinki, Finland
[5] Univ Helsinki, Translat Immunol Res Program, Helsinki, Finland
[6] Helsinki Univ Hosp, Helsinki, Finland
[7] Helsinki Univ Hosp, Dept Oncol, Comprehens Canc Ctr, Helsinki, Finland
来源：
BLOOD | 2022年 / 140卷
关键词：
D O I：
10.1182/blood-2022-166768
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：5889 / 5890
页数：2
相关论文
共 50 条
  • [1] Disruption of KLHL6 Fuels Oncogenic Antigen Receptor Signaling in B-Cell Lymphoma
    Meriranta, Leo
    Sorri, Selma
    Huse, Kanutte
    Liu, Xiaonan
    Spasevska, Ivana
    Zafar, Sadia
    Chowdhury, Iftekhar
    Dufva, Olli
    Sahlberg, Eerika
    Tandaric, Luka
    Karjalainen-Lindsberg, Marja-Liisa
    Hyytiainen, Marko
    Varjosalo, Markku
    Myklebust, June H.
    Leppa, Sirpa
    BLOOD CANCER DISCOVERY, 2024, 5 (05): : 331 - 352
  • [2] KLHL6 is a tumor suppressor gene in diffuse large B-cell lymphoma
    Choi, Jaewoo
    Zhou, Nan
    Busino, Luca
    CELL CYCLE, 2019, 18 (03) : 249 - 256
  • [3] B-Cell Receptor Signaling in Diffuse Large B-Cell lymphoma
    Young, Ryan M.
    Shaffer, Arthur L., III
    Phelan, James D.
    Staudt, Louis M.
    SEMINARS IN HEMATOLOGY, 2015, 52 (02) : 77 - 85
  • [4] Tonic B-cell receptor signaling in diffuse large B-cell lymphoma
    Havranek, Ondrej
    Xu, Jingda
    Koehrer, Stefan
    Wang, Zhiqiang
    Becker, Lisa
    Comer, Justin M.
    Henderson, Jared
    Ma, Wencai
    Ma, John Man Chun
    Westin, Jason R.
    Ghosh, Dipanjan
    Shinners, Nicholas
    Sun, Luhong
    Yi, Allen F.
    Karri, Anusha R.
    Burger, Jan A.
    Zal, Tomasz
    Davis, R. Eric
    BLOOD, 2017, 130 (08) : 995 - 1006
  • [5] Low Expression and Somatic Mutations of the KLHL6 Gene Predict Poor Survival in Patients with Activated B-Cell like Diffuse Large B-Cell Lymphoma
    Meriranta, Leo
    Pasanen, Annika
    Cervera, Alejandra
    Holte, Harald, Jr.
    Lehtonen, Rainer
    Hautaniemi, Sampsa
    Leppa, Sirpa
    BLOOD, 2016, 128 (22)
  • [6] B-Cell Receptor Signaling Modulates Cholesterol Biosynthesis in Diffuse Large B-Cell Lymphoma
    Agarwal, Nitin
    Aradhya, Akanksha
    Marques-Piubelli, Mario L.
    Soto, Luisa M. Solis
    Bilbao, Daniel
    Landgraf, Ralf
    Ravanmehr, Vida
    Henderson, Jared
    Green, Michael R.
    Davis, Eric
    Vega, Francisco
    BLOOD, 2022, 140 : 1320 - 1321
  • [7] B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma
    Ci, Weimin
    Polo, Jose M.
    Melnick, Ari
    CURRENT OPINION IN HEMATOLOGY, 2008, 15 (04) : 381 - 390
  • [8] Targeting the B-cell receptor pathway in diffuse large B-cell lymphoma
    Dunleavy, Kieron
    Erdmann, Tabea
    Lenz, Georg
    CANCER TREATMENT REVIEWS, 2018, 65 : 41 - 46
  • [9] Antigen-Independent, Autonomous B-Cell Receptor Signaling in Diffuse Large B-Cell Lymphoma
    Eken, Janneke A.
    Koning, Marvyn T.
    Yanez, Julieta H. Sepulveda
    van Bergen, Cornelis A. M.
    Quinten, Edwin
    Kupcova, Kristyna
    Havranek, Ondrej
    De Groen, Ruben A. L.
    Vermaat, Joost S. P.
    de Jong, Daphne
    Kluin, Philip
    Cleven, Arjen
    Jumaa, Hassan
    Veelken, Hendrik
    BLOOD, 2022, 140 : 6444 - 6445
  • [10] Diffuse large B-cell lymphoma - Molecular heterogeneity of diffuse large B-cell lymphoma
    Gascoyne, RD
    HEMATOLOGY JOURNAL, 2004, 5 : S144 - S148
12345