Advances in Early Detection of Pancreatic Cancer

被引:36
|
作者
Kanno, Atsushi [1 ,2 ]
Masamune, Atsushi [1 ]
Hanada, Keiji [2 ,3 ]
Kikuyama, Masataka [2 ,4 ]
Kitano, Masayuki [2 ,5 ]
机构
[1] Tohoku Univ, Grad Sch Med, Div Gastroenterol, Aoba Ku, 1-1 Seiryo Machi, Sendai, Miyagi 9808574, Japan
[2] Japan Study Grp Early Detect Pancreat Canc JEDPAC, Onomichi 7228508, Japan
[3] JA Onomichi Gen Hosp, Dept Gastroenterol, Onomichi 7228508, Japan
[4] Tokyo Metropolitan Canc & Infect Dis Komagome Hos, Dept Gastroenterol, Tokyo 1130021, Japan
[5] Wakayama Med Univ, Sch Med, Dept Gastroenterol, Wakayama 6410012, Japan
基金
日本学术振兴会;
关键词
pancreatic ductal cell carcinoma; PDAC; early stage; ERCP; HIGH-RISK; DIABETES-MELLITUS; EARLY-DIAGNOSIS; MULTICENTER; CARCINOMA; EUS;
D O I
10.3390/diagnostics9010018
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease. PDAC is the fourth leading cause of death in the United States and Japan based on epidemiological data. Early detection of PDAC is very important to improve the prognosis of PDAC. Early detection of pancreatic ductal adenocarcinoma (PDAC) requires further examination after selecting cases with risk factors for the condition, such as family history, hereditary pancreatic carcinoma syndrome, intraductal papillary mucinous neoplasms, or chronic pancreatitis. The Japan Study Group on the Early Detection of Pancreatic Cancer has investigated and clarified the clinicopathological features for the early diagnosis of PDAC. In Japan, an algorithm for the early diagnosis of PDAC, which utilized the cooperation of local clinics and regional general hospitals, has been a breakthrough in the detection of early-stage PDAC. Further approaches for the early diagnosis of PDAC are warranted.
引用
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页数:11
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