Protein-DNA interaction: impedance study of MutS binding to a DNA mismatch

被引:44
|
作者
Li, CZ
Long, YT
Lee, JS
Kraatz, HB
机构
[1] Univ Saskatchewan, Dept Biochem, Saskatoon, SK S7N 5E5, Canada
[2] Univ Saskatchewan, Dept Chem, Saskatoon, SK S7N 5C9, Canada
关键词
D O I
10.1039/b314642a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
MutS binding to a double-stranded DNA containing a single nucleotide mismatch can be conveniently monitored by impedance spectroscopy and represents the first step in developing an electrochemical binding essay for single nucleotide mismatch detection.
引用
收藏
页码:574 / 575
页数:2
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