Impact of junctional ectopic tachycardia on postoperative morbidity following repair of congenital heart defects

被引:79
|
作者
Dodge-Khatami, A
Miller, OI
Anderson, RH
Gil-Jaurena, JM
Goldman, AP
de Leval, MR
机构
[1] Great Ormond St Hosp Children NHS Trust, Cardiothorac Unit, London WC1N 3JH, England
[2] Univ London, Inst Child Hlth, London WC1N 1EH, England
关键词
junctional ectopic tachycardia; postoperative morbidity; congenital heart defects;
D O I
10.1016/S1010-7940(01)01089-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To determine the incidence of postoperative junctional ectopic tachycardia (JET), we reviewed 343 consecutive patients undergoing surgery between 1997 and 1999. The impact of this arrhythmia on inhospital morbidity and our protocol for treatment were assessed. Methods: We reviewed the postoperative course of patients undergoing surgery for ventricular septal defect (VSD; n = 161), tetralogy of Fallot (TOF; n = 114), atrioventricular septal defect (AVSD; n = 58) and common arterial trunk (n = 10). All patients with JET received treatment, in a stepwise manner, beginning with surface cooling, continuous intravenous amiodarone, and/or atrial pacing if the haemodynamics proved unstable. A linear regression model assessed the effect of these treatments upon hours of mechanical ventilation, and stay on the cardiac intensive care unit (CICU). Results: Overall mortality was 2.9% (n = 10), with three of these patients having JET and TOF. JET occurred in 37 patients (10.8%), most frequently after TOF repair (21.9%), followed by AVSD (10.3%), VSD (3.7%), and with no occurrence after repair of common arterial trunk. Mean ventilation time increased from 83 to 187 h amongst patients without and with JET patients (P < 0.0001). Accordingly, CICU stay increased from 107 to 210 h when JET occurred (P < 0.0001). Surface cooling was associated with a prolongation of ventilation and CICU stay, by 74 and 81 h, respectively (P < 0.02; P < 0.02). Amiodarone prolonged ventilation and CICU stay, respectively, by 274 and 275 h (P < 0.05; P < 0.06). Conclusions: Postoperative JET adds considerably to morbidity after congenital cardiac surgery, and is particularly frequent after TOF repair. Aggressive treatment with cooling and/or amiodarone is mandatory, but correlates with increased mechanical ventilation time and CICU stay. Better understanding of the mechanism underlying JET is required to achieve prevention, faster arrhythmic conversion, and reduction of associated inhospital morbidity. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:255 / 259
页数:5
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