Chemical toxicity on HeLa cells

被引：14

作者：

Verma, RP ^{[1
]}

Hansch, C ^{[1
]}

机构：

[1] Pomona Coll, Dept Chem, Claremont, CA 91711 USA

来源：

CURRENT MEDICINAL CHEMISTRY | 2006年 / 13卷 / 04期

关键词：

QSAR; hydrophobicity; molar refractivity; molar volume; Verloop's sterimol; Hammett parameters;

D O I：

10.2174/092986706775527910

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

HeLa cells were named for Henrietta Lacks, who died in 1952 from an infection of a special type of cancer. Margaret Gey, her physician, started working with these cancer cells that are still used for medical research. In the present review, an attempt has been made to collect the data for the effects of different chemicals on HeLa cells and to discuss them by the formulation of a total number of 22 QSAR.

引用

页码：423 / 448

页数：26

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