Initial Results of the Phase I/II Panobidara Study of Panobinostat in Combination with Idarubicin and Cytarabine in Patients Aged 65 Years or Older with Newly Diagnosed Acute Myeloblastic Leukaemia (AML)

被引：0

作者：

Ocio, Enrique M. ^{[1
]}

Herrera, Pilar ^{[2
]}

Olave, Teresa ^{[3
]}

Brunet, Salut ^{[4
]}

Oriol, Albert ^{[5
]}

Martinez-Sanchez, Maria-Pilar ^{[6
]}

Sanz, Miguel A. ^{[7
]}

Mateos, Marta ^{[8
]}

Aliseda, Pilar ^{[9
]}

Winiger, Ivo J. ^{[10
]}

Hardikar, Sushant ^{[11
]}

Victoria Mateos, Maria ^{[1
]}

Lopez, Javier ^{[2
]}

San-Miguel, Jesus F. ^{[1
]}

机构：

[1] Hosp Univ Salamanca, Inst Invest Biomed Salamanca IBSAL, Salamanca, Spain

[2] Hosp Univ Ramon y Cajal, Serv Hematol & Hemoterapia, Madrid, Spain

[3] HCU Lozano Blesa, Zaragoza, Spain

[4] Hosp Santa Creu & Sant Pau, Barcelona, Spain

[5] H Germans Trias & Pujol, Hematol, Badalona, Spain

[6] Hosp Univ 12 Octubre, Madrid, Spain

[7] Hosp Univ la Fe, Valencia, Spain

[8] Hosp Clin San Carlos, Madrid, Spain

[9] Novartis Farmaceut SA, Madrid, Spain

[10] Novartis Pharma AG, Basel, Switzerland

[11] Novartis Pharmaceut, E Hanover, NJ USA

来源：

BLOOD | 2012年 / 120卷 / 21期

关键词：

D O I：

10.1182/blood.V120.21.1512.1512

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

1512

引用

页数：2

共 50 条

[1] PHASE I/II PANOBIDARA STUDY OF PANOBINOSTAT IN COMBINATION WITH IDARUBICIN AND CYTARABINE IN PATIENTS AGED 65 YEARS OR OLDER WITH NEWLY DIAGNOSED ACUTE MYELOBLASTIC LEUKAEMIA (AML)
Ocio, E. M.
Herrera, P.
Olave, M. T.
Martinez, M. P.
Perez-Simon, J. A.
Brunet, S.
Oriol, A.
Mateos, M.
Sanz, M. A.
Lopez, J.
Mateos, M. V.
San Miguel, J. F.
[J]. HAEMATOLOGICA, 2014, 99 : 527 - 527
[2] Interim results of a phase I/II randomized study of clofarabine, idarubicin, and cytarabine (CIA) versus fludarabine, idarubicin, and cytarabine (FIA) for newly diagnosed or relapsed patients (pts) with acute myeloid leukemia (AML).
Mathisen, Michael
Kantarjian, Hagop
Faderl, Stefan
Garcia-Manero, Guillermo
Ravandi, Farhad
Kadia, Tapan M.
Daver, Naval Guastad
O'Brien, Susan Mary
Dorkhom, Stephan Joseph
Pierce, Sherry
Lira, Cynthia
Cortes, Jorge E.
Jabbour, Elias
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
[3] Phase 2 Study of Combination of Cytarabine, Idarubicin, and Nivolumab for Initial Therapy of Patients with Newly Diagnosed Acute Myeloid Leukemia
Ravandi, Farhad
Daver, Naval
Garcia-Manero, Guillermo
Benton, Christopher B.
Thompson, Philip A.
Borthakur, Gautam
Kadia, Tapan
Boddu, Prajwal C.
Alvarado, Yesid
Jabbour, Elias J.
Konopleva, Marina
Takahashi, Koichi
Kornblau, Steven
DiNardo, Courtney D.
Estrov, Zeev
Flores, Wilmer
Basu, Sreyashi
Allison, James
Sharma, Padmanee
Pierce, Sherry
Brandt, Mark
Pike, Allison
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[J]. BLOOD, 2017, 130
[4] Combination of Sorafenib, Idarubicin, and Cytarabine Has a High Response Rate in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) Younger Than 65 Years
Ravandi, Farhad
Cortes, Jorge
Faderl, Stefan
Garcia-Manero, Guillermo
O'Brien, Susan
Borthakur, Gautam
Pierce, Sherry
Brandt, Mark
Lang, Marites
Zhang, Weiguo
Luthra, Rajyalakshmi
Jones, Dan
Levis, Mark J.
Konopleva, Marina
Andreeff, Michael
Kantarjian, Hagop M.
[J]. BLOOD, 2008, 112 (11) : 285 - 285
[5] Phase 2 Study of the Combination of Cytarabine, Idarubicin , acid Niyolumab for Initial Therapy of Patients With Newly Diagnosed Acute Myeloid Leukemia
不详
[J]. CLINICAL ADVANCES IN HEMATOLOGY & ONCOLOGY, 2018, 16 (03) : 7 - 9
[6] Panobinostat as part of induction and maintenance for elderly patients with newly diagnosed acute myeloid leukemia: phase Ib/II panobidara study
Ocio, Enrique M.
Herrera, Pilar
Olave, Maria-Teresa
Castro, Nerea
Perez-Simon, Jose A.
Brunet, Salut
Oriol, Albert
Mateo, Marta
Sanz, Miguel-Angel
Lopez, Javier
Montesinos, Pau
Chillon, Maria-Carmen
Prieto-Conde, Maria-Isabel
Diez-Campelo, Maria
Gonzalez, Marcos
Vidriales, Maria-Belen
Mateos, Maria-Victoria
San Miguel, Jesus F.
[J]. HAEMATOLOGICA, 2015, 100 (10) : 1294 - 1300
[7] INDOXIMOD IN COMBINATION WITH IDARUBICIN AND CYTARABINE FOR UPFRONT TREATMENT OF PATIENTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA (AML): PHASE 1 REPORT
Emadi, A.
Holtzman, N. G.
Imran, M.
El Chaer, F.
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Singh, Z.
Shahlaee, A.
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Duong, V. H.
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Link, C.
[J]. HAEMATOLOGICA, 2017, 102 : 375 - 375
[8] Updated Results of a Phase I/II, Randomized Study of Clofarabine Combined with Idarubicin and Cytarabine (CIA) or Fludarabine Combined with Idarubicin and Cytarabine (FIA) for the Treatment of Patients (pts) with Newly Diagnosed or Relapsed/Refractory (RR) Acute Myeloid Leukemia (AML)
Mathisen, Michael S.
Kantarjian, Hagop M.
Ravandi, Farhad
Pemmaraju, Naveen
Garcia-Manero, Guillermo
Cortes, Jorge E.
O'Brien, Susan
Quintas-Cardama, Alfonso
Ghanem, Hady
Daver, Naval G.
Pierce, Sherry A.
Lira, Cynthia
Faderl, Stefan
Jabbour, Elias
[J]. BLOOD, 2012, 120 (21)
[9] Remission induction in newly diagnosed AML patients aged 55-75 years using a 5 day idarubicin schedule in combination with cytarabine
Douer, D
Saven, A
Watkins, K
Gollard, R
Kahn, A
Piro, L
Levine, AM
[J]. BLOOD, 1995, 86 (10) : 3015 - 3015
[10] Updated Results of a Randomized Phase II Trial of Idarubicin and Cytarabine with Clofarabine or Fludarabine in Patients with Newly Diagnosed Acute Myeloid Leukemia
Short, Nicholas J.
Ravandi, Farhad
Huang, Xuelin
Cortes, Jorge E.
Pemmaraju, Naveen
Daver, Naval
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Jain, Nitin
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Kadia, Tapan M.
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[J]. BLOOD, 2016, 128 (22)

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