Synthesis and physicochemical properties of the pectin complexes with Xymedon

被引:2
|
作者
Minzanova, S. T. [1 ]
Mironov, V. F. [1 ]
Khabibullina, A., V [1 ]
Arkhipova, D. M. [1 ]
Mironova, L. G. [1 ]
Ryzhkina, I. S. [1 ]
Sergeeva, S. Yu [1 ]
Murtazina, L., I [1 ]
Smolobochkina, F. R. [1 ]
Milyukov, V. A. [1 ]
机构
[1] Russian Acad Sci, AE Arbuzov Inst Organ & Phys Chem, Fed Res Ctr, Kazan Sci Ctr, 8 Ul Akad Arbusova, Kazan 420088, Russia
关键词
pectin; Xymedon; complexation; POLYSACCHARIDE; CA;
D O I
10.1007/s11172-019-2400-z
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The formation of stable complexes of pectin polysaccharides with 1-(2-hydroxyethyl)-4,6-dimethyl-1,2-dihydropyrimidin-2-one (Xymedon drug) was shown by UV and IR spectro scopy, dynamic light scattering, and polarimetry. The stoichiometry of the complexes was determined, and their synthesis conditions were optimized. Specific features of the thermal decomposition of pectin and synthesized complexes with Xymedon were studied by the TG/DSC method. The results obtained allow one to substantially extend ranges of using Xymedon in medicine.
引用
收藏
页码:405 / 410
页数:6
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