Herpes zoster burden of illness and health care resource utilisation in the Australian population aged 50 years and older

被引:83
|
作者
Stein, Alicia N. [1 ]
Britt, Helena [4 ]
Harrison, Christopher [4 ]
Conway, E. Lynne [1 ]
Cunningham, Anthony [3 ]
MacIntyre, C. Raina [2 ]
机构
[1] CSL Ltd, Parkville, Vic 3052, Australia
[2] Univ New S Wales, Sch Publ Hlth & Community Med, Sydney, NSW 2052, Australia
[3] Univ Sydney, Westmead Millennium Inst, Sydney, NSW 2006, Australia
[4] Univ Sydney, Sch Publ Hlth, Australian Gen Practice Stat & Classificat Ctr, Sydney, NSW 2006, Australia
关键词
Herpes zoster; Post-herpetic neuralgia; Burden of illness; Health care costs; POSTHERPETIC NEURALGIA; VIRUS-INFECTION; VARICELLA; VACCINE; IMMUNOGENICITY; EPIDEMIOLOGY; PATHOGENESIS; MANAGEMENT; DIAGNOSIS; SAFETY;
D O I
10.1016/j.vaccine.2008.11.012
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Incidence of zoster and post-herpetic neuralgia (PHN) and associated health care resource Utilisation were investigated in the Australian population aged >= 50 years, using general Practice data from 2000 to 2006, and pharmaceutical prescribing, hospital morbidity and emergency department data from 1998 to 2005. Zoster and PHN incidence rates were estimated as similar to 10/1000 and 1.45/1000 persons, respectively, with antivirals prescribed for 73.5% of zoster cases. Estimated hospitalisation and emergency department visit rates were 0.67/1000 and 0.38/1000 persons, respectively. Management of zoster (including PHN) involved similar to 2.4 general practitioner consultations. Total costs to the health care system were estimated as similar to 32.8 million per year. The Substantial burden of zoster and PHN highlights the potential benefit of zoster vaccination. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:520 / 529
页数:10
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