Bioinspired antifouling polymers

被引:200
|
作者
Dalsin, Jeffrey L. [1 ]
Messersmith, Phillip B. [1 ]
机构
[1] Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA
基金
美国国家卫生研究院; 美国国家航空航天局;
关键词
D O I
10.1016/S1369-7021(05)71079-8
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Controlling biointerfacial phenomena is crucial to the success of many biomedical technologies. For applications in biosensing, diagnostics, and medical devices, precise control of interactions between material surfaces and the biological milieu is an important but elusive goal(1). Emerging strategies for manipulating the biological response to medical materials seek to take advantage of specific interactions between designed surfaces, biomolecules, and cells(2). Limiting nonspecific interaction of cells, proteins, and microorganisms with material surfaces is critical, since these interactions can prove highly problematic for device efficacy and safety. Thus, a central research focus continues to be the development of versatile, convenient, and cost-effective strategies for rendering surfaces resistant to fouling by proteins, cells, and bacteria.
引用
收藏
页码:38 / 46
页数:9
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