Clinical impact of 18F-FDG PET in management of patients with renal cell carcinoma

被引：21
|
作者：
Rodriguez Martinez de Llano, S. [1 ]
Jimenez-Vicioso, A. [2 ]
Mahmood, S.
Carreras-Delgado, J. L. [3 ]
机构：
[1] Ctr Oncol Galicia, Nucl Med Serv, La Coruna, Spain
[2] Univ Complutense Madrid, Fac Med, Dept Radiol, E-28040 Madrid, Spain
[3] Hosp Clin San Carlos, Nucl Med Serv, Madrid, Spain
来源：
REVISTA ESPANOLA DE MEDICINA NUCLEAR | 2010年 / 29卷 / 01期
关键词：
Renal cancer; Renal cell carcinoma; Clinical impact; PET; FDG; F-18-FDG PET; POSITRON-EMISSION-TOMOGRAPHY; DISTANT METASTASES; C-11-ACETATE PET; CANCER; PROSTATE; STRATIFICATION; PREDICTION; SUNITINIB; EFFICACY; BLADDER;
D O I：
10.1016/j.remn.2009.11.008
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
We performed a retrospective study to evaluate the accuracy, diagnostic validity, and clinical impact of F-18-FDG PET in the management of recurrent and metastatic disease in patients with Renal Cell Carcinoma (RCC) from our database. F-18-FDG PET studies were identified from 58 patients that matched our criteria for inclusion in the study. Results were confirmed with histopathological findings, clinical follow-up time (at least 12 months), and/ or conventional imaging methods (CIM). A sensitivity of 80.56%, specificity 86.36%, diagnostic accuracy 58.7%, positive predictive value 90.63%, and a negative predictive value of 73.08% were observed. The clinical impact was high in 25 cases (43%) and we found no impact in only 10 studies (17.2%), We concluded that 18F-FDG PET was useful and had a high clinical impact in the management of recurrent and metastatic RCC. From our data, it seemed that a positive PET study was more helpful to the physician than a negative study. (C) 2009 Elsevier Espana, S.L. y SEMNIM. All rights reserved.
引用
收藏
页码：12 / 19
页数：8
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