Miliary tuberculosis leading to acute respiratory distress syndrome: Clinical experience in pediatric intensive care

被引:5
|
作者
Piastra, Marco [1 ,2 ]
Picconi, Enzo [1 ]
Morena, Tony C. [1 ]
Valentini, Piero [3 ]
Buonsenso, Danilo [3 ]
Conti, Giorgio [1 ,2 ]
Antonelli, Massimo [2 ]
Wolfler, Andrea M. [4 ]
Chidini, Giovanna [5 ]
Pons-Odena, Marti [6 ]
De Pascale, Gennaro [2 ]
Gemelli, Policlinico A.
Valentini, Piero [3 ]
Lancella, Laura [7 ]
Marano, Marco [7 ]
Genovese, Orazio [1 ]
De Luca, Daniele [1 ]
Luca, Ersilia [1 ]
Morena, Tony C. [1 ]
Marzano, Laura [1 ]
Picconi, Enzo [1 ]
Pizza, Alessandro [1 ]
Biasucci, Daniele G. [2 ]
Gelormini, Camilla [2 ]
Buonsenso, Danilo [3 ]
Tempera, Alessia [3 ]
De Carolis, Maria P. [3 ]
机构
[1] Univ Cattolica Sacro Cuore, Fdn Policlin A Gemelli, Pediat ICU & Trauma Ctr, Rome, Italy
[2] Univ Cattolica Sacro Cuore, Fdn Policlin A Gemelli, Dept Anesthesiol & Intens Care, Rome, Italy
[3] Univ Cattolica Sacro Cuore, Fdn Policlin A Gemelli, Dept Pediat, Rome, Italy
[4] ICP, V Buzzi Pediat Hosp, Intens Care Unit, Milan, Italy
[5] De Marchi Policlin Univ, Pediat Intens Care Unit, Milan, Italy
[6] Sant Joan de Deu Pediat Hosp, Intens Care Unit, Barcelona, Spain
[7] Bambino Gesu Pediat Hosp, Rome, Italy
关键词
ARDS; HFOV; intratracheal surfactant; miliary tuberculosis; nebulized DNAase; Pott disease; VENTILATION; ARDS;
D O I
10.1002/ppul.24510
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Acute respiratory distress syndrome (ARDS) represents a rare complication of miliary tuberculosis (TB) in the adult setting, and it is even less common in the pediatric population. The presence of comorbidities and the possibility of a delayed diagnosis may further impair the clinical prognosis of critically ill patients with disseminated TB and acute respiratory failure. In this report, we present a case series of five pediatric patients with miliary TB and ARDS, where rescue and multimodal respiratory support strategies have been applied with a favorable outcome in more than half of them. The burden of miliary TB over time on a general pediatric intensive care unit-including two ARDS patients-is also illustrated.
引用
收藏
页码:2003 / 2010
页数:8
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