Newcastle disease virus (strain Herts 33/56) in tissues and organs of chickens infected experimentally

被引:19
|
作者
Alexander, DJ [1 ]
Manvell, RJ [1 ]
Parsons, G [1 ]
机构
[1] Vet Labs Agcy Weybridge, Dept Virol, Addlestone KT15 3NB, Surrey, England
关键词
D O I
10.1080/03079450600597444
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Six-week-old susceptible specific pathogen free chickens were infected intranasally with the virulent Newcastle disease virus strain Herts 33/56 and the levels of virus present in blood, faeces, breast muscle, leg muscle and a pool of heart/kidney/spleen were estimated in birds killed humanely at each day post inoculation. Highest titres were recorded at day 4 post inoculation when titres of virus were 10(6) median egg infectious doses ( EID50)/g in the heart/kidney/spleen pool, 10(4.2) EID50/g in the leg muscle and 10(4) EID50/g in the breast muscle and faeces. A median oral infectious dose of Newcastle disease virus strain Herts 33/56 for 3-week-old chickens was estimated to be equivalent to 10(4) EID50.
引用
收藏
页码:99 / U7
页数:4
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