Investigation of sol-gel derived silicate glasses loaded with vitamin C

This study is focused on entrapping the vitamin C (ascorbate) into silicate matrices prepared via sot-gel method, and on evaluation of ascorbate influence on the glass matrices and conversely. Silicate glasses of SiO2 and 56SiO(2)-40CaO-4P(2)O(5) compositions were loaded with vitamin C for potential application as biomaterials in tissue regeneration. The changes induced in vitamin C and in glass matrices by loading with vitamin C were analyzed using DTA, XRD, BET methods, and FTIR spectroscopy. Surface area and pore volume diminish in both samples as loaded with vitamin C, while the thermal stability of vitamin C is increased by entrapment in sol-gel derived silicate.