A decreasing feeding profile for the optimization of ethanol production in a recombinant Escherichia coli fed-batch fermentation

被引:4
|
作者
Saucedo, VM [1 ]
Karim, MN [1 ]
机构
[1] COLORADO STATE UNIV,DEPT CHEM & BIORESOURCE ENGN,FT COLLINS,CO 80523
关键词
D O I
10.1007/BF00129731
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
A decreasing feed flowrate was used to optimize the ethanol volumetric productivity and was found to be optimal and equal to 1.8 g ethanol/h . L with a recombinant Escherichia coli with plasmid pLOI297. This productivity is more than double in previous reports. High substrate concentrations favor ethanol production when the microorganisms are in the exponential phase and when they are not inhibited.
引用
收藏
页码:1055 / 1060
页数:6
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