Modeling of a Nanofilter and Its Application to the Separation of DNA

被引：0

作者：

Park, Pyeong Jun ^{[1
]}

机构：

[1] Korea Natl Univ Transportat, Sch Liberal Arts & Sci, Chungju 27469, South Korea

来源：

JOURNAL OF THE KOREAN PHYSICAL SOCIETY | 2018年 / 72卷 / 02期

关键词：

Master equation; Nanofilter; DNA Separation Resolution; POLYMER; ELECTROPHORESIS; DYNAMICS; KRAMERS;

D O I：

10.3938/jkps.72.320

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We consider a nanofilter device that has been used experimentally for separation of DNA (Deoxyribonucleic acid) with different lengths less than thousands of base pairs. We introduce a master equation for describing the dynamics of DNA in a nanofilter under an external electric field, and obtain the probability distribution of DNA for a given nanofilter geometry. Our results are consistent with experimental results and provide an estimate of the minimum device size required to obtain the target separation resolution in the separation of DNA.

引用

页码：320 / 325

页数：6

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