A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity

被引：19

作者：

Pejin, Boris ^{[1
,2
,3
]}

Tommonaro, Giuseppina ^{[1
]}

Iodice, Carmine ^{[1
]}

Tesevic, Vele ^{[2
]}

Vajs, Vlatka ^{[4
]}

De Rosa, Salvatore ^{[1
]}

机构：

[1] Natl Res Council Italy, Inst Biomol Chem, CNR ICB, Naples, Italy

[2] Univ Belgrade, Fac Chem, Dept Organ Chem, YU-11001 Belgrade, Serbia

[3] Univ Belgrade, Inst Multidisciplinary Res, Dept Life Sci, Belgrade, Serbia

[4] Univ Belgrade, Ctr Chem, Inst Chem Technol & Met, YU-11001 Belgrade, Serbia

来源：

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | 2013年 / 28卷 / 04期

关键词：

Lichen; secondary metabolite; biological activity;

D O I：

10.3109/14756366.2012.677839

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The phytochemical investigation conducted on a foliose lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), led to the isolation of a new depsidone in the form of its diacetate derivative which showed a moderate acetylcholinesterase inhibition activity (1 mu g) in vitro. This is the first record of identified depsidone structure in searching for these inhibitors.

引用

页码：876 / 878

页数：3

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